METHOD AND APPARATUS FOR PERSONALIZED PHYSIOLOGIC PARAMETERS
First Claim
1. An apparatus to monitor a patient, the apparatus comprising:
- at least two electrodes coupled to circuitry to measure an impedance of the patient;
at least one processor to receive the measured impedance and patient data, the at least one processor configured to determine an output based on the impedance and the patient data.
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Accused Products
Abstract
Methods and apparatus combine patient measurement data with demographic or physiological data of the patient to determine an output that can be used to diagnose and treat the patient. A customized output can be determined based the demographics of the patient, physiological data of the patient, and data of a population of patients. In another aspect, patient measurement data is used to predict an impending cardiac event, such as acute decompensated heart failure. At least one personalized value is determined for the patient, and a patient event prediction output is generated based at least in part on the personalized value and the measurement data. For example, bioimpedance data may be used to establish a baseline impedance specific to the patient, and the patient event prediction output generated based in part on the relationship of ongoing impedance measurements to the baseline impedance. Multivariate prediction models may enhance prediction accuracy.
199 Citations
86 Claims
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1. An apparatus to monitor a patient, the apparatus comprising:
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at least two electrodes coupled to circuitry to measure an impedance of the patient; at least one processor to receive the measured impedance and patient data, the at least one processor configured to determine an output based on the impedance and the patient data. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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35. A method of monitoring a patient, the method comprising:
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measuring an impedance of the patient; and determining a patient output based on the measured impedance and a patient data.
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36. An apparatus to monitor a patient having a body fluid, the apparatus comprising:
means for determining an output based on patient data.
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37. A method of predicting an impending patient cardiac event, the method comprising:
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receiving impedance data measured from the patient; establishing at least one patient-specific value for the patient based at least in part on the impedance data; and generating, based at least in part on the impedance data and the at least one patient-specific value, a patient event prediction output predictive of the impending patient cardiac event. - View Dependent Claims (38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62)
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63. A system for predicting a cardiac event of a patient, the system comprising;
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an adherent device attachable to a patient to electronically measure impedance data from the patient; and a processor and a tangible memory readable by the processor; wherein the memory stores instructions that, when executed by the processor, cause the system to receive the impedance data; establish at least one personalized value for the patient based on the impedance data; and generate, based at least in part on the impedance data and the at least one personalized value, a patient event prediction output predictive of a patient cardiac event. - View Dependent Claims (64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78)
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79. A system for measuring an impedance parameter of a patient, the system comprising:
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a processor and a tangible memory readable by the processor; and an input mechanism for receiving a series of samples of the patient'"'"'s bioimpedance; wherein the memory stores instructions that, when executed by the processor, cause the system to receive the series of samples of the patient'"'"'s bioimpedance; and derive the impedance parameter from the series of samples. - View Dependent Claims (80, 81)
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82. A system for measuring a breath parameter of a patient, the system comprising:
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a processor and a tangible memory readable by the processor; and an input mechanism for receiving a series of samples of the patient'"'"'s bioimpedance; wherein the memory stores instructions that, when executed by the processor, cause the system to receive the series of samples of the patient'"'"'s bioimpedance; and derive the breath parameter from the series of samples. - View Dependent Claims (83, 84, 85, 86)
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Specification