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OLIGOMERIC BIOSURFACTANTS IN DERMATOCOSMETIC COMPOSITIONS

  • US 20110250153A1
  • Filed: 05/29/2009
  • Published: 10/13/2011
  • Est. Priority Date: 06/01/2006
  • Status: Active Grant
First Claim
Patent Images

1. An oligomeric acylated biosurfactant having a critical micelle concentration of less than about 200 ppm in an aqueous environment of MEM Solution that reduces the surface tension of the MEM Solution to less than about 50 dynes/cm2 where the OAB consists essentially of (i) an 8- to 22-membered carbon chain, branched or unbranched, saturated or unsaturated;

  • (ii) three to nine amino acid residues, at least one of which is charged; and

    (iii) an acid C-terminus or an amide C-terminus where the oligomeric acylated biosurfactant is selected from the group consisting of;

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    Myr-Gly-Ala-Arg-acid;

    Myr-Ala-His-Arg-amide;

    Myr-Arg-Arg-Arg-amide;

    Myr-Lys-Lys-Lys-acid;

    Myr-Asp-Ala-Asp-acid;

    Myr-Ala-His-Arg-acid;

    Pal-Gly-Arg-Lys-amide;

    Myr-Lys-His-Arg-amide;

    Pal-Ala-His-Arg-amide;

    Myr-Lys-Lys-Lys-amide;

    Pal-Lys-Lys-Lys-amide;

    Myr-Ser-Asp-Asp-acid;

    Myr-Gly-His-Arg-amide;

    Pal-Gly-His-Arg-amide;

    Myr-Gly-Arg-Lys-amide; and

    Pal-Gly-His-[arg]D-amide.

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