METHODS AND SYSTEMS FOR NON-INVASIVE TREATMENT OF TISSUE USING HIGH INTENSITY FOCUSED ULTRASOUND THERAPY
First Claim
1. A method of non-invasively treating tissue, the method comprising:
- positioning a focus of an ultrasound source at a target site in tissue, the ultrasound source being configured to emit high intensity focused ultrasound (HIFU) waves;
pulsing ultrasound energy from the ultrasound source toward the target site; and
generating shock waves in the tissue to induce boiling of the tissue at the target site, wherein boiling the tissue at least substantially emulsifies the tissue.
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Abstract
Methods and systems for non-invasive treatment of tissue using high intensity focused ultrasound (“HIFU”) therapy. A method of non-invasively treating tissue in accordance with an embodiment of the present technology, for example, can include positioning a focal plane of an ultrasound source at a target site in tissue. The ultrasound source can be configured to emit HIFU waves. The method can further include pulsing ultrasound energy from the ultrasound source toward the target site, and generating shock waves in the tissue to induce boiling of the tissue at the target site within milliseconds. The boiling of the tissue at least substantially emulsifies the tissue.
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Citations
29 Claims
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1. A method of non-invasively treating tissue, the method comprising:
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positioning a focus of an ultrasound source at a target site in tissue, the ultrasound source being configured to emit high intensity focused ultrasound (HIFU) waves; pulsing ultrasound energy from the ultrasound source toward the target site; and generating shock waves in the tissue to induce boiling of the tissue at the target site, wherein boiling the tissue at least substantially emulsifies the tissue. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method treating tissue at a target site, the method comprising:
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treating the target site with high intensity focused ultrasound (HIFU), wherein the HIFU is delivered from an ultrasound source, and wherein the HIFU is delivered using a pulsing protocol with individual pulse lengths between approximately 1 ms and approximately 100 ms; and forming a lesion at the target site in the tissue, wherein the lesion is formed by shock waves generated proximate to the target site that induce boiling of the tissue at the target site, and wherein the target site is proximate to a focal plane of the ultrasound source. - View Dependent Claims (16, 17, 18, 19, 20, 21)
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22. A high intensity focused ultrasound (HIFU) system for treating tissue, the HIFU system comprising:
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an ultrasound source having a frequency range between approximately 0.5 MHz and approximately 20 MHz, the ultrasound source being configured to deliver a peak positive pressure of between approximately 10 MPa and 100 MPa; and a function generator operably coupled to the ultrasound source, the function generator being configured to generate a pulsing protocol delivered by the ultrasound source to a target site of tissue, wherein the pulsing protocol comprises at least one of ultrasound source frequency, peak positive pressure, pulse length, shock wave amplitude, pulse repetition frequency, and duty cycle. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29)
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Specification