RAPID DELIVERY AND/OR WITHDRAWAL OF FLUIDS
5 Assignments
0 Petitions
Accused Products
Abstract
The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.
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Citations
168 Claims
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1-148. -148. (canceled)
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149. A device applicable to the skin of a subject, the device comprising:
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a reversibly deformable structure; and one or more needles, at least some of which comprise a coating, fastened to a deformable portion of the deformable structure, wherein, when the device is applied to the surface of the skin of a subject and the structure is deformed, the one or more needles are driven into the skin of the subject. - View Dependent Claims (150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162)
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163. A device applicable to the skin of a subject, the device comprising:
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a support structure; and one or more needles, at least some of which comprise a coating, fastened to the support structure, wherein the support structure is able to insert the one or more needles into the skin at a speed of at least about 1 cm/s. - View Dependent Claims (164, 165, 166, 167, 168)
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Specification