FEEDBACK SYSTEM FOR INTEGRATING INTERVENTIONAL PLANNING AND NAVIGATION

• US 20110251607A1
• Filed: 11/05/2009
• Published: 10/13/2011
• Est. Priority Date: 12/03/2008
• Status: Active Grant

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.), United States Department Of Health And Human Services
• Original Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Inventors: Wood, Bradford J., Kruecker, Jochen, Xu, Sheng, Dalal, Sandeep
• Granted Patent: US 9,144,461 B2
• Time in Patent Office: Days
• US Class Current: 606/34
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2018/1425 Needle
• CPC Class Codes: A61B 2034/104 Modelling the effect of the tool, e.g. the effect of an implanted prosthesis or for predicting the effect of ablation or burring
• CPC Class Codes: A61B 2034/107 Visualisation of planned trajectories or target regions
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

A therapy planning and image guidance and navigation for an interventional procedure are combined in one system. The system includes: a radio frequency ablation therapy planning component (1) capable of creating an initial treatment plan, adjusting the treatment plan to take into account data received during a procedure and transferring a treatment plan to a navigation component, a navigation system component (2) to guide an ablation probe (6) and a feedback sub-system (3) for determining actual ablation probe positions/orientations and actual ablation size/shape via imaging (4) and/or tracking (5) systems, and enabling exchange of information between the planning component and the navigation component. By combining and integrating procedure planning and navigation, and by providing feedback from the navigation component back to the planning component about actual electrode position and orientation and ablation volume, complex procedures can be carried out more accurately, efficiently, and potentially with better clinical outcomes.

Claims

1. A system for ablation treatment of tissue, comprising:

an ablation probe (6) for treating a tissue of interest with at least one of RF ablation, cryo-ablation, microwave ablation, ultrasound ablation, or other thermal or non-thermal ablation;

a planning component (1) for calculating a three-dimensional treatment plan including a plurality of desired ablation probe placement positions and orientations and a plurality of estimated ablation volumes to achieve a composite ablation volume that will treat the entire planned target volume (PTV);

a navigation component (2) for spatially tracking at least one of the treatment probe and an imaging device and providing treatment instructions to an operator based on the three-dimensional treatment plan;

an imaging component (4) for obtaining planning and treatment images of the tissue to be treated; and

a feedback component (3) for determining actual probe position and orientation using the navigation component or imaging component, and for determining actual ablation volume based on treatment images provided by the imaging component (4), and feeding the actual probe position and orientation and actual ablation volume during treatment to the planning component (1),

wherein the planning component (1) determines a treatment iteration based on the treatment plan, the actual probe position and orientation and actual ablation volume, the treatment iteration including at least one of a desired next probe position and orientation and a desired next ablation volume, and

wherein the navigation component (2) provides revised treatment instructions to the operator based on the treatment iteration until treatment is completed according to the desired planned target volume.

2. The system according to claim 1, wherein the imaging component (4) provides at least one of ultrasound, CT, MR imaging, ultrasound elastography, and Doppler ultrasound, and wherein the navigation component provides at least one of spatial tracking coordinates of the therapy probe and imaging, based on at least one of electromagnetic (EM), optical, acoustic, and magnetic tracking sensors.

3. The system according to claim 1, further comprising a user interface for displaying the treatment iteration instructions from the navigation component (2) for access by a human operator.

4. The system according to claim 1, wherein the feedback component (3) further calculates at least one of local micro-vascular perfusion and macro-vascular blood flow parameters near the ablation site and provides this information to the planning component (1) for incorporation into the treatment iteration.

5. The system according to claim 1, wherein the feedback component (3) registers treatment images with planning images to calculate at least one of the actual probe position and orientation and tumor position and orientation, and uses the information to update the three-dimensional treatment plan.

6. The system according to claim 1, wherein the feedback component (3) obtains imaging feedback and tracking feedback about the actual probe location, and uses the information to update and improve the registration between the imaging system and tracking system

7. A method of ablation therapy of tissue, comprising:

calculating a three-dimensional treatment plan (20) for a tissue of interest including a plurality of desired ablation probe placement positions and orientations and a plurality of estimated ablation volumes to achieve a desired planned target volume that will treat the entire tissue volume of interest;

providing treatment instructions (14) to an operator based on the three-dimensional treatment plan;

treating the tissue of interest with at least one of RF ablation, cryo-ablation, microwave ablation, ultrasound ablation, and other thermal or non-thermal ablation;

obtaining planning (10) and treatment images of the tissue to be treated;

determining actual probe position and orientation and actual ablation volume (30) based on the treatment images; and

calculating a treatment iteration (32) based on the treatment plan, the actual probe position and orientation and actual ablation volume, the treatment iteration including at least one of a desired next probe position and a desired next ablation volume, and

providing revised treatment instructions to the operator based on the treatment iteration and continuing iterative treatment until treatment is completed according to the desired planned target volume.

8. The method according to claim 7, wherein the imaging component provides at least one of ultrasound, CT, MR imaging, ultrasound elastography, and Doppler ultrasound, and wherein the navigation component provides at least one of spatial tracking coordinates of the therapy probe and imaging based on at least one of electromagnetic (EM), optical, acoustic, and magnetic sensors.

9. The method according to claim 7, wherein the treatment is carried out by a human operator accessing at least one of the treatment plan and the treatment iteration instructions from a user interface.

10. The method according to claim 7, wherein at least one of local micro-vascular perfusion and macro-vascular blood flow parameters near the ablation site are calculated, and this information is incorporated into the treatment iteration.

11. The method according to claim 7, wherein the treatment images are registered with planning images to calculate at least one of the actual probe position and orientation and tumor position and orientation, and to use the information to update the three-dimensional treatment plan.

12. The method according to claim 7, wherein treatment images showing the actual ablation probe location and tracking system data representing the actual probe position are used to update the registration between the imaging system and tracking system.

13. A control system for ablation treatment of tissue, comprising:

a planning component (1) for calculating a three-dimensional treatment plan including a plurality of desired ablation probe placement positions and orientations and a plurality of estimated ablation volumes to achieve a desired planned target volume that will treat an entire tissue volume of interest;

an imaging component (4) for obtaining treatment images of the tissue to be treated; and

a feedback component (3) for calculating actual probe position and orientation and actual ablation volume based on treatment images provided by the imaging component, and feeding the actual probe position and orientation and actual ablation volume during treatment to the planning component,

wherein the planning component (1) maps the actual probe location and actual ablation volume to the three-dimensional plan and calculates a treatment iteration based on the treatment plan, the actual probe position and orientation and actual ablation volume, the treatment iteration including at least one of a desired next probe position and orientation and a desired next ablation volume.

14. The control system according to claim 13, wherein the imaging component (4) provides at least one of ultrasound, CT, MR imaging, ultrasound elastography, and Doppler ultrasound, and wherein the navigation component provides at least one of spatial tracking coordinates of the therapy probe and imaging device based on at least one of electromagnetic (EM), optical, acoustic, and magnetic sensors.

15. The control system according to claim 13, wherein the control system delivers the next treatment ablation according to the calculated treatment iteration by at least one of moving the ablation probe to the desired next probe position and ablating the next desired ablation volume.

16. The control system according to claim 13, wherein the feedback component (3) further calculates at least one of local micro-vascular perfusion and macro-vascular blood flow parameters near the ablation site and provides this information to the planning component for incorporation into the treatment iteration.

17. The control system according to claim 13, wherein the feedback component (3) registers treatment images with planning images to calculate at least one of the actual probe position and orientation and tumor position and orientation, and uses the information to update the three-dimensional treatment plan.

18. The control system according to claim 13, wherein the feedback component (3) obtains imaging feedback and tracking feedback about the actual probe location, and uses the information to update and improve the registration between the imaging system and tracking system.

19. The control system according to claim 14, wherein the imaging component (4) utilizes a contrast medium.

20. The control system according to claim 13, wherein the planning component (1) utilizes center positions of individual ablations for calculating the three-dimensional treatment plan.