Planning for adaptive radiotherapy
First Claim
1. An optimization method of a fluence pattern, to be provided by a radiotherapy apparatus to a patient, wherein a first fluence pattern is calculated based on a first image of a treatment area of the patient and one or more geometric constraints of the radiotherapy apparatus, and wherein generation of the first fluence pattern involves the calculation of one or more Lagrange multipliers, the method comprising:
- after a period of treatment, obtaining a second image of the treatment area of the patient; and
using the second image and said one or more Lagrange multipliers to generate a second fluence pattern.
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Abstract
The present invention provides a method for updating and optimizing a treatment plan for radiotherapy. An initial treatment plan, calculated using a constraint-driven method, may be updated using a weighted-sum method, where Lagrange multipliers generated in the constraint method are reused as the weights for the weighted sum. This method results in acceptable updated treatment plans that are generated in a small fraction of the time taken to generate an entirely new treatment plan, reducing patient discomfort and ensuring the radiotherapy facility can treat more patients.
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Citations
12 Claims
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1. An optimization method of a fluence pattern, to be provided by a radiotherapy apparatus to a patient, wherein a first fluence pattern is calculated based on a first image of a treatment area of the patient and one or more geometric constraints of the radiotherapy apparatus, and wherein generation of the first fluence pattern involves the calculation of one or more Lagrange multipliers, the method comprising:
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after a period of treatment, obtaining a second image of the treatment area of the patient; and using the second image and said one or more Lagrange multipliers to generate a second fluence pattern. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An optimization method for a radiotherapy treatment plan, for delivery of a therapeutic dose of radiation by a radiotherapy apparatus to a patient, the method comprising:
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obtaining a first image of an area of the patient, the area including at least a target region for a therapeutic dose of radiation, and one or more regions sensitive to radiation; using the first image and one or more geometric constraints of the radiotherapy apparatus to generate a first treatment plan, in which radiation is delivered to the target region at a first, relatively high intensity, and radiation is delivered to the one or more sensitive regions at a second, relatively low intensity; obtaining a second image of the area of the patient; and using the second image and one or more Lagrange multipliers found in the generation of the first treatment plan to form a second treatment plan.
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12. A computer program product for optimizing a fluence pattern, to be provided by a radiotherapy apparatus to a patient, wherein a first fluence pattern is calculated based on a first image of a treatment area of the patient and one or more geometric constraints of the radiotherapy apparatus, and wherein generation of the first fluence pattern involves the calculation of one or more Lagrange multipliers, the computer program product comprising:
- a computer readable storage medium having a computer program stored thereon for performing the steps of;
receiving second image data of the treatment area of the patient; and using the second image and said one or more Lagrange multipliers to form a second fluence pattern.
- a computer readable storage medium having a computer program stored thereon for performing the steps of;
Specification