PHOTOTHERAPY FOR RENAL DENERVATION
First Claim
1. An apparatus for facilitating delivery of optical energy to a renal artery of a patient, comprising:
- a catheter configured for deployment relative to the renal artery;
an optical fiber arrangement supported by the catheter and comprising a coupling for receiving laser light from a laser light source; and
an optics arrangement supported by the catheter and coupled to the optical fiber arrangement, the optics arrangement comprising one or more optical elements arranged to receive the laser light and project optical energy to a desired depth within innervated tissue at or proximate an outer wall of the renal artery, the optical energy of sufficient power to ablate innervated tissue at or proximate the outer wall of the renal artery.
1 Assignment
0 Petitions
Accused Products
Abstract
Apparatuses and methods facilitate delivery of optical or photoacoustic energy to innervated vascular that contributes to renal sympathetic nerve activity. The optical energy delivered may be of sufficient power to scan or image innervated renal or aortal tissue. The optical energy delivered may be of sufficient power to ablate innervated renal or aortal tissue, such as by thermal laser ablation or photoacoustic laser ablation. A catheter for intravascular or extravascular deployment supports an optical fiber arrangement comprising a coupling for receiving light from a laser light source. An optics arrangement is supported by the catheter and coupled to the optical fiber arrangement. The optics arrangement includes one or more optical elements arranged to receive the laser light and direct optical energy to target innervated tissue or a water source from which a cavitation bubble may be created and launched for acoustically shocking the target innervated tissue.
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Citations
20 Claims
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1. An apparatus for facilitating delivery of optical energy to a renal artery of a patient, comprising:
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a catheter configured for deployment relative to the renal artery; an optical fiber arrangement supported by the catheter and comprising a coupling for receiving laser light from a laser light source; and an optics arrangement supported by the catheter and coupled to the optical fiber arrangement, the optics arrangement comprising one or more optical elements arranged to receive the laser light and project optical energy to a desired depth within innervated tissue at or proximate an outer wall of the renal artery, the optical energy of sufficient power to ablate innervated tissue at or proximate the outer wall of the renal artery. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. An apparatus for facilitating delivery of optical energy to a renal artery of a patient, comprising:
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a catheter configured for intravascular deployment within a lumen of the renal artery; an optical fiber arrangement supported by the catheter and comprising a coupling for receiving laser light from a laser light source; an optics arrangement supported by the catheter and coupled to the optical fiber arrangement, the optics arrangement comprising one or more optical elements arranged to receive the laser light; and a balloon arrangement dimensioned for deployment within the lumen of the renal artery and comprising a fluid vessel containing at least water, the balloon arrangement encompassing at least a portion of the optical fiber arrangement and the optics arrangement, the optical fiber and optics arrangements configured to direct optical energy to the fluid vessel sufficient to create a cavitation bubble therein, the fluid vessel serving to direct an acoustic shock wave generated by bursting of the cavitation bubble to innervated target tissue of the renal artery.
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20. An apparatus for facilitating delivery of optical energy to a renal artery of a patient, comprising:
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a catheter configured for intravascular deployment within a lumen of the renal artery; a phototherapy unit provided at a distal end of the catheter, the phototherapy unit comprising a light source configured to generate white light of an intensity sufficient to ablate innervated tissue of the renal artery; and a balloon arrangement dimensioned for deployment within the lumen of the renal artery and encompassing at least a portion of the phototherapy unit that comprises the white light source, the balloon comprising; a reflector arrangement disposed on a region of the balloon proximate the phototherapy unit, the reflector arrangement serving to direct white light generated by the light source to innervated target tissue of the renal artery; and a thermal transfer arrangement configured to provide cooling to renal artery tissue adjacent the balloon.
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Specification