DIALYSIS PROBE

• US 20110259811A1
• Filed: 04/19/2011
• Published: 10/27/2011
• Est. Priority Date: 04/26/2010
• Status: Abandoned Application

• Current Assignee: Eicom Corporation, Osaka University
• Original Assignee: Eicom Corporation, Osaka University
• Inventors: IKIMURA, Kazuko, SATO, Naoyuki, MORISHITA, Ryuichi, NISHINO, Hirohito, TAKEDA, Shuko
• Application Number:
  US13/089,536
• Publication Number:
  US 20110259811A1
• Time in Patent Office: Days
• US Class Current: 210/444
• CPC Class Codes: A61B 5/14528 invasively
• CPC Class Codes: A61B 5/4064 Evaluating the brain A61B5/031, A61B5/369, A61B5/14553 take precedence
• CPC Class Codes: A61B 5/6846 specially adapted to be brought in contact with an internal body part, i.e. invasive

Abstract

Provided is a dialysis probe capable of stably performing an analysis with high accuracy for a long period of time even if the inflow and outflow rates of a perfusate are not completely equalized.

A dialysis probe 1 according to the present invention includes a tubular dialysis membrane 2 sealed at its tip, a support tube 3 coupled at a tip to a rear end of the dialysis membrane 2, a cap portion 4 for securing a rear end of the support tube 3, an inlet conduit 5 extending through the cap portion 4 toward the tip of the dialysis membrane 2 within a space 10 to guide a perfusate into the space 10, an outlet conduit 6 extending through the cap portion 4 toward the tip of the dialysis membrane 2 within the space 10 to guide the perfusate in the space 10 outside the space 10, and at least one air-exposure through-hole 7 provided in the cap portion 4 for maintaining the space 10 at atmospheric pressure, and the inlet conduit 5 has a longer protruding length from the rear end of the support tube 3 when compared to the outlet conduit 6.

Claims

1. A dialysis probe comprising:

a tubular dialysis membrane sealed at its tip;

a support tube coupled at a tip to a rear end of the dialysis membrane;

a cap portion for securing a rear end of the support tube;

an inlet conduit for guiding a perfusate into a space enclosed by the dialysis membrane, the support tube, and the cap portion, the inlet conduit extending through the cap portion toward the tip of the dialysis membrane within the space;

an outlet conduit for guiding the perfusate in the space outside the space, the outlet conduit extending through the cap portion toward the tip of the dialysis membrane within the space; and

at least one air-exposure through-hole provided in the cap portion for maintaining the space at atmospheric pressure, wherein,

the inlet conduit has a longer protruding length from the rear end of the support tube when compared to the outlet conduit, and an outflow rate of the perfusate exiting the space through the outlet conduit is set to be greater than or equal to an inflow rate of the perfusate entering the space through the inlet conduit.

2. The dialysis probe according to claim 1, wherein the dialysis membrane and the support tube are joined by an adhesive layer provided between an outer circumferential surface of the dialysis membrane and an inner circumferential surface of the support tube.

3. A dialysis probe comprising:

a tubular dialysis membrane open at opposite ends;

an inlet conduit coupled at a tip to one end of the dialysis membrane so as to guide a perfusate into a space within the dialysis membrane; and

an outlet conduit for guiding the perfusate in the space within the dialysis membrane outside the space, the outlet conduit extending from the space in an opposite direction to the inlet conduit, wherein,

the space is exposed to air, and an outflow rate of the perfusate exiting the space through the outlet conduit is set to be greater than or equal to an inflow rate of the perfusate entering the space through the inlet conduit.

4. The dialysis probe according to claim 3, further comprising an air-exposure tube extending from the space in the same direction as the outlet conduit.

5. The dialysis probe according to claim 3, further comprising an extension tube concentrically coupled to the other end of the dialysis membrane and extending in an axial direction of the dialysis membrane, wherein,

the outlet conduit extends inside the extension tube.

6. The dialysis probe according to claim 3, wherein the inlet conduit and the dialysis membrane are joined by an adhesive layer provided between an outer circumferential surface of the inlet conduit and an inner circumferential surface of the dialysis membrane.

7. The dialysis probe according to claim 5, wherein the extension tube and the dialysis membrane are joined by an adhesive layer provided between an outer circumferential surface of the extension tube and an inner circumferential surface of the dialysis membrane, and the extension tube and the outlet conduit are partially joined by an adhesive layer provided between a portion of an inner circumferential surface of the extension tube and a portion of an outer circumferential surface of the outlet conduit.