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OIL-BASED FOAMABLE CARRIERS AND FORMULATIONS

  • US 20110268665A1
  • Filed: 10/06/2009
  • Published: 11/03/2011
  • Est. Priority Date: 12/07/2007
  • Status: Active Grant
First Claim
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1. A waterless foamable pharmaceutical composition, comprising a foamable carrier and at least one liquefied or compressed gas propellant wherein the foamable carrier consists essentially of:

  • about 60% to about 98% by weight of at least one liquid oil; and

    about 2% to about 40% by weight of a surfactant, wherein the surfactant comprises at least a glyceride; and

    optionally an additive selected from the group consisting of a foam adjuvant, a polymer stabilizer, a thickener, and mixtures thereof;

    wherein the ingredients are compatible with a minocycline antibiotic; and

    wherein the foamable carrier is substantially a single phase, is in a compatible canister and wherein upon dispensing the foamable carrier composition forms a breakable foam that is thermally stable, yet breaks easily upon application of shear force.

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