MESOPOROUS NANOPARTICLES

• US 20110268970A1
• Filed: 07/07/2011
• Published: 11/03/2011
• Est. Priority Date: 07/06/2004
• Status: Abandoned Application

• Current Assignee: Agency For Science Technology and Research (Government of Singapore)
• Original Assignee: Agency For Science Technology and Research (Government of Singapore)
• Inventors: YING, Jackie Y., HAN, Yu
• Application Number:
  US13/177,886
• Publication Number:
  US 20110268970A1
• Time in Patent Office: Days
• US Class Current: 428/402
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics
• CPC Class Codes: A61P 31/18 for HIV
• CPC Class Codes: A61P 35/00 Antineoplastic agents
• CPC Class Codes: A61P 5/00 Drugs for disorders of the endocrine system
• CPC Class Codes: A61P 9/12 Antihypertensives
• CPC Class Codes: B01J 21/08 Silica
• CPC Class Codes: B01J 29/0308 Mesoporous materials not having base exchange properties, e.g. Si-MCM-41
• CPC Class Codes: B01J 35/647 2-50 nm
• CPC Class Codes: B82Y 10/00 Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
• CPC Class Codes: B82Y 30/00 Nanotechnology for materials or surface science, e.g. nanocomposites
• CPC Class Codes: C01B 37/00 Compounds having molecular sieve properties but not having base-exchange properties
• CPC Class Codes: C01B 37/02 Crystalline silica-polymorphs, e.g. silicalites dealuminated aluminosilicate zeolites
• CPC Class Codes: Y10T 428/2982 Particulate matter [e.g., sphere, flake, etc.]

Abstract

The present invention provides a process for making mesoporous nanoparticles. The process comprises providing an acidic mixture comprising a fluorocarbon surfactant, a second surfactant and a silica precursor. The silica precursor is then reacted to form the mesoporous nanoparticles.

Claims

1-31. -31. (canceled)

32. Mesoporous nanoparticles when made by a process comprising:

providing an acidic mixture comprising a fluorocarbon surfactant, a second surfactant and a silica precursor; and

reacting the silica precursor to form the mesoporous nanoparticles.

33. The mesoporous nanoparticles of claim 32, each having a particle size between about 1 and about 500 nm and a mean pore size between about 1 and about 50 nm.

34. The mesoporous nanoparticles of claim 33 wherein the pore size is between about 10 and about 50 nm.

35. The mesoporous nanoparticles of claim 32, each having a particle size between about 32 and about 500 nm and having a mesostructure selected from the group consisting of 3-D cubic, 3-D foam-like, 2-D hexagonal and wormlike.

36. The mesoporous nanoparticle of claim 35 wherein the pore size is greater than about 10 nm.

37. Mesoporous nanoparticles according to claim 32, when used in an application selected from the group consisting of catalysis, gas adsorption, synthesis of quantum dots and magnetic nanoparticles in functional materials and bioimaging applications, and as carriers for drugs, genes and proteins for biomedical applications.

38. Mesoporous nanoparticles according to claim 32, said nanoparticles having a species selected from the group consisting of a drug, a gene and a protein associated therewith.

39. Mesoporous nanoparticles according to claim 32 which are spherical and/or round ended cylinders.

40. Mesoporous nanoparticles according to claim 32 comprising silica doped with another element.

41. Mesoporous nanoparticles according to claim 32 having a catalytic species adsorbed or bound or sorbed on and/or in the nanoparticles.

42. Mesoporous nanoparticles according to claim 41 wherein the catalytic species is selected from the group consisting of an organic catalytic species, an organometallic catalytic species, an inorganic catalytic species and an enzyme.

43. Mesoporous nanoparticles according to claim 32 having a drug and/or a gene and/or a protein associated therewith.

44. Regular shaped mesoporous nanoparticles having a particle size between about 32 and about 500 nm and having a mesostructure selected from the group consisting of 3-D cubic, 3-D foam-like, 2-D hexagonal and wormlike.

45. Nanoparticles according to claim 44 which are spherical and/or round ended cylinders.

46. Nanoparticles according to claim 44 having a pore size between about 10 and about 50 nm.

47. Nanoparticles according to claim 44, said nanoparticles having a species selected from the group consisting of a drug, a gene and a protein associated therewith.

48. Nanoparticles according to claim 44, having a catalytic species adsorbed or bound or sorbed on and/or in the nanoparticle.

49. Nanoparticles according to claim 48 wherein the catalytic species is selected from the group consisting of an organic catalytic species, an organometallic catalytic species, an inorganic catalytic species and an enzyme.