Apparatus for treatment of dermatological conditions

• US 20110269693A1
• Filed: 07/18/2011
• Published: 11/03/2011
• Est. Priority Date: 10/11/2004
• Status: Active Grant

• Current Assignee: CareWear Corp.
• Original Assignee: Dermaglaia, Ltd.
• Inventors: Luebcke, Peter
• Granted Patent: US 10,406,383 B2
• Time in Patent Office: Days
• US Class Current: 514/18.8
• CPC Class Codes: A61N 2007/0008 Destruction of fat cells
• CPC Class Codes: A61N 2007/0073 using multiple frequencies
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 7/00 Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 3/04 Anorexiants; Antiobesity agents
• CPC Class Codes: A61P 43/00 Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

This invention relates to ultrasound delivery apparatus comprising flexible arrays of transducers and to methods and topical compositions for the treatment of skin, in particular for the treatment of cosmetic skin conditions and to improve the appearance of sun damaged and/or aged skin; the invention further relates to the use of such apparatus and compositions in methods of treating skin, which methods may incorporate the application of ultrasound. The composition may comprise one or more anti-gfycation agent, one or more anti-oxidant, a dermatologically acceptable excipient and optionally one or more substance capable of inducing expression of a molecular chaperone.

Claims

1. An apparatus for application of ultrasound to the skin comprising a plurality of ultrasound transducer elements arranged as an array in a flexible material in spaced configuration, wherein the ultrasound transducer elements are capable of delivering ultrasound at low and/or high frequency to an area of the skin.

2. An apparatus according to claim 1, wherein the ultrasound transducer elements are capable of delivering low and high frequency ultrasound simultaneously or sequentially.

3. An apparatus according to claim 1, wherein the transducer elements are dual frequency transducer elements capable of delivering low and high frequency ultrasound sequentially or simultaneously.

4. An apparatus according to claim 3, wherein the dual frequency transducer elements are capable of delivering low and high frequency ultrasound along a common axis.

5. A dual frequency transducer element comprising a high frequency transducer element and a low frequency transducer element.

6. A composition comprising one or more anti-glycation agent, one or more anti-oxidant, a dermatologically acceptable excipient and optionally one or more substance capable of inducing expression of a molecular chaperone.

7. A method for treatment of the skin, comprising applying to the skin a composition according to claim 6.

8. The use of a composition according to claim 6 in the manufacture of a composition for the treatment of a skin condition.

9. A dressing comprising a composition according to claim 6.

10. A kit comprising a composition according to claim 6 and a device comprising an ultrasound source and/or an applicator for applying ultrasound to the skin and/or for applying the composition to the skin.