Ingestion-Related Biofeedback and Personalized Medical Therapy Method and System

• US 20110270052A1
• Filed: 01/06/2010
• Published: 11/03/2011
• Est. Priority Date: 01/06/2009
• Status: Active Grant

• Current Assignee: Proteus Digital Health, Inc. (Otsuka Holdings Company Limited)
• Original Assignee: Proteus Digital Health, Inc. (Otsuka Holdings Company Limited)
• Inventors: Arne, Lawrence, Au-Yeung, Kit Yee, Beaulieu, Patrick, Behzadi, Yashar, Savage, George, Thompson, Andrew, Leichner, Robert, Robertson, Timothy, Zdeblick, Mark, Jensen, Marc
• Granted Patent: US 9,883,819 B2
• Time in Patent Office: Days
• US Class Current: 600/302
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/073 Intestinal transmitters
• CPC Class Codes: A61B 5/1112 Global tracking of patients, e.g. by using GPS
• CPC Class Codes: A61B 5/486 Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/00 ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 20/30 relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass
• CPC Class Codes: H04B 13/005 Transmission systems in which the medium consists of the human body
• CPC Class Codes: H04L 67/12 specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks

Abstract

Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.

Claims

1. A system comprising:

an ingestible event marker associated with communicated information; and

an analysis module comprising a wireless transceiver to receive the communicated information, wherein the analysis module incorporates at least one datum of the communicated information in an analysis of a health parameter of a patient.

2. The system of claim 1, wherein the at least one datum specifies a biometric information descriptive of the patient.

3. The system of claim 1, wherein the analysis module is communicatively coupled to a determination module to determine a therapeutic recommendation, wherein the therapeutic recommendation is generated at least partly on the basis of the analysis of a health parameter of a patient.

4. The system of claim 2, further comprising a communication device to communicate the therapeutic recommendation to the patient as transmitted from the wireless transceiver of the analysis module.

5. The system of claim 4, wherein the communication device is selected from the group consisting essentially of a telephone, a cellular telephone, a computer, a personal digital assistant, and a network appliance.

6. The system of claim 3, wherein the determination module generates the therapeutic determination at least partly on the basis of the at least one datum and a genetic information descriptive of the patient.

7. The system of claim 3, wherein the determination module generates the therapeutic determination at least partly on the basis of the at least one datum and the biometric information in view of an additional patient information.

8. The system of claim 7, wherein the additional patient information is selected from the group consisting essentially of lifestyle data, patient adherence to a therapy information, behavioral information, emotional information and diagnostic test information.

9. The system of claim 3, wherein the therapeutic recommendation is selected from the recommendation group essentially consisting of a medicine prescription adjustment, a meditation practice, a relaxation practice, a physical exercise, procedural change, therapy change and a dietary adjustment.

10. The system of claim 3, further comprising a motion detector coupled with the patient for generating a patient motion datum, wherein the motion detector is communicatively coupled to the analysis module and the analysis module incorporates the patient motion datum in an analysis of at least one health parameter of a patient.

11. The system of claim 10, wherein the motion detector is selected from the group consisting of a cellular telephone, an accelerometer and a global positioning signal device.

12. The system of claim 1, wherein the system further comprises:

a patient management data system communicatively coupled to the analysis module; and

a vital parameter monitor to monitor a health parameter of the patient and communicatively coupled with the patient management data system.

13. The system of claim 12, wherein the vital parameter monitor is selected from the group consisting essentially of a heart rate monitor, a blood pressure monitor, a respiration monitor, and a patient skin electrical current conductivity monitor

14. The system of claim 12, further comprising a patient data input module to receive information from the patient, the patient data input module communicatively coupled with the patient management data system.

15. The system of claim 14, wherein the patient data input module is bi-directionally communicatively coupled with the patient management data system.

16. The system of claim 14, wherein the patient data input module is selected from the group consisting essentially of a telephone, a cellular telephone, a computer, a personal digital assistant, a network appliance, and an audio recorder.

17. The system of claim 12, wherein the patient management data system stores at least one behavioral suggestion that includes an instruction to engage in a behavior intended to improve a condition in a human patient.

18. The system of claim 12, further comprising a motion detector to detect and report movement of the patient to the patient management data system.

19. The system of claim 12, wherein the patient management data system is communicatively coupled with an electronic communications network and an instruction to engage in behavior intended to improve a condition of the patient is received by the patient management data system from the electronic communications network.

20. A system comprising:

an ingestible event marker associated with communicated information;

a patient management data system comprising a wireless transceiver to receive the communicated information and a patient messaging module to provide a behavioral suggestion to a patient;

a vital parameter monitoring system communicatively coupled with the patient management data system to monitor a vital parameter of the patient; and

a database associated with the patient management data system to store the vital parameter and health data associated with the patient, wherein the patient management data system generates and communicates at least one behavioral suggestion to the patient based on an analysis of the vital parameter, the communicated information and the health data associated with the patient.