PROCESS FOR SYNTHESIZING OXIDIZED LACTAM COMPOUNDS
First Claim
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1. A method for preparing a compound of Formula I, comprising the step of reacting a compound of Formula IA:
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Abstract
The invention provides a method for the synthesis of dehydrogenated lactam drugs of Formula I:
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17 Claims
- 1. A method for preparing a compound of Formula I, comprising the step of reacting a compound of Formula IA:
- 2. A method for preparing a compound of Formula III, comprising the step of reacting a compound of Formula IIIA:
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3. A method for preparing a compound of Formula IV, comprising the step of reacting a compound of Formula IVA:
- 4. A method for preparing a compound of Formula V, comprising the step of reacting a compound of Formula VA:
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10. A method for preparing a compound of Formula VI, comprising the step of reacting a compound of Formula VIA with a compound of Formula II in the presence of an acid:
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11. A method for preparing a compound of Formula VII, comprising the step of reacting a compound of Formula VIIA with a compound of Formula II in the presence of an acid:
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12. A method for preparing a compound of Formula VIII, comprising the step of reacting a compound of Formula VIIIA in the presence of an acid:
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