VASCULAR STENT DESIGN

• US 20110276123A1
• Filed: 11/25/2008
• Published: 11/10/2011
• Est. Priority Date: 11/27/2007
• Status: Abandoned Application

• Current Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Original Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Inventors: Davies, Peter F., Jimenez, Juan M.
• Application Number:
  US12/744,871
• Publication Number:
  US 20110276123A1
• Time in Patent Office: Days
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61F 2250/0013 for adjusting fluid pressure

Abstract

This invention is directed to the design of radially expandable vascular stents to optimize hemodynamic flow characteristics that are favorable for the inhibition of stent-associated thrombosis, inflammation, and restenosis (neointimal formation) and that will reduce the risk of adverse events post-deployment.

Claims

5-1. The stent of claim 1 wherein said strut has an outer surface whose contour in the longitudinal direction substantially corresponds to the radius of curvature of a lumen within which said stent is implanted.

7. A method of ensuring flow over a stent that is substantially free of disturbed flow, comprising:

implanting in a predetermined location in a coronary or peripheral artery a stent providing attached or minimally separated blood flow therethrough, said stent comprising one of more struts each having a leading section and a trailing section in the direction of blood flow through said stent, said strut comprising;

a cross-sectional geometry longitudinally disposed thereon for blood flow thereover, comprising a leading section and a trailing section with a continuous surface contour with varying slope throughout,

wherein the leading subsection introduces a favorable pressure gradient over the leading section of the strut affecting a directional change in blood flow without resulting in blood flow separation, the trailing section affects a directional change in blood flow without inducing blood flow separation, and a midsection disposed therebetween, thereby providing attached or minimally separated blood flow over each said stent strut and throughout the length of the stent.