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METHODS OF REPROGRAMMING CELLS

  • US 20110280842A1
  • Filed: 08/24/2009
  • Published: 11/17/2011
  • Est. Priority Date: 08/22/2008
  • Status: Active Grant
First Claim
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1. A method for reprogramming a cell of endoderm origin, the method comprising increasing the protein expression of at least two transcription factors selected from Pdx1, Ngn3, or MafA in the cell of enodermal origin, wherein the cell of enodermal origin is reprogrammed to exhibit at least two characteristics of a pancreatic β

  • -cell.

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