ENCAPSULATION OF PANCREATIC CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS
First Claim
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1. A cell encapsulating assembly for implanting into a mammalian host, said assembly comprising at least one chamber for encapsulating living cells, wherein the assembly comprises a first seal at a peripheral edge of the assembly, thereby forming the encapsulating assembly, and a second seal which effectively reduces the chamber volume but increases device surface area.
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Abstract
The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation.
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Citations
8 Claims
- 1. A cell encapsulating assembly for implanting into a mammalian host, said assembly comprising at least one chamber for encapsulating living cells, wherein the assembly comprises a first seal at a peripheral edge of the assembly, thereby forming the encapsulating assembly, and a second seal which effectively reduces the chamber volume but increases device surface area.
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8. A device comprising:
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a sealed edge; and a cell encapsulating chamber interior to said sealed edge, wherein said cell encapsulating chamber is disposed between said sealed edge and a partition seal, said partition seal interesting with not more than one sealed edge of the device.
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Specification