SYSTEMS AND METHODS TO DETERMINE OPTIMAL DIAMETERS OF VESSEL SEGMENTS IN BIFURCATION

• US 20110282586A1
• Filed: 05/12/2011
• Published: 11/17/2011
• Est. Priority Date: 01/23/2007
• Status: Abandoned Application

• Current Assignee: DTherapeutics LLC
• Original Assignee: DTherapeutics LLC
• Inventors: Huo, Yunlong, Kassab, Ghassan S.
• Application Number:
  US13/106,035
• Publication Number:
  US 20110282586A1
• Time in Patent Office: Days
• US Class Current: 702/19
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/026 Measuring blood flow A61B3/1233, A61B3/1241 take precedence
• CPC Class Codes: A61B 5/1076 for measuring dimensions inside body cavities, e.g. using catheters A61B3/1005 takes precedence

Abstract

Systems and methods to determine optimal diameters of vessel segments in bifurcation. In at least one embodiment of a method for determining a diameter of a segment of a bifurcated vessel of the present disclosure, the method comprises the steps of identifying a diameter of a first segment of a bifurcated vessel, identifying a diameter of a second segment of the bifurcated vessel, and determining a diameter of a third segment of the bifurcated vessel based upon the diameter of the first segment and the diameter of the second segment, wherein the determination is further based upon an exponential relationship of or about 7/3 for each diameter.

Claims

1. A method for determining a diameter of a segment of a bifurcated vessel, the method comprising the steps of:

identifying a diameter of a first segment of a bifurcated vessel;

identifying a diameter of a second segment of the bifurcated vessel; and

determining a diameter of a third segment of the bifurcated vessel based upon the diameter of the first segment and the diameter of the second segment, wherein the determination is further based upon an exponential relationship of or about 7/3 for each diameter.

2. The method of claim 1, wherein the diameter of a first segment of a bifurcated vessel is a diameter of a mother bifurcation segment, wherein the diameter of a second segment of a bifurcated vessel is a diameter of a larger daughter bifurcation segment, and wherein the diameter of a third segment of a bifurcated vessel is a diameter of a smaller daughter bifurcation segment.

3. The method of claim 2, wherein the step of determining a diameter of a third segment of the bifurcated vessel is performed by subtracting a 7/3 exponent of the diameter of the second segment from a 7/3 exponent of the diameter of the first segment to obtain a 7/3 exponent of the diameter of a smaller daughter bifurcation segment, or by performing a mathematical equivalent thereof.

4. The method of claim 3, wherein the diameter of a smaller daughter bifurcation segment can be obtained by calculating a 7/3 root of the obtained 7/3 exponent of the diameter of a smaller daughter bifurcation segment.

5. The method of claim 1, wherein the diameter of a first segment of a bifurcated vessel is a diameter of a smaller daughter bifurcation segment, wherein the diameter of a second segment of a bifurcated vessel is a diameter of a mother bifurcation segment, and wherein the diameter of a third segment of a bifurcated vessel is a diameter of a larger daughter bifurcation segment.

6. The method of claim 5, wherein the step of determining a diameter of a third segment of the bifurcated vessel is performed by subtracting a 7/3 exponent of the diameter of the first segment from a 7/3 exponent of the diameter of the second segment to obtain a 7/3 exponent of the diameter of a larger daughter bifurcation segment, or by performing a mathematical equivalent thereof.

7. The method of claim 6, wherein the diameter of a larger daughter bifurcation segment can be obtained by calculating a 7/3 root of the obtained 7/3 exponent of the diameter of a larger daughter bifurcation segment.

8. The method of claim 1, wherein the diameter of a first segment of a bifurcated vessel is a diameter of a larger daughter bifurcation segment, wherein the diameter of a second segment of a bifurcated vessel is a diameter of a smaller daughter bifurcation segment, and wherein the diameter of a third segment of a bifurcated vessel is a diameter of a mother bifurcation segment.

9. The method of claim 8, wherein the step of determining a diameter of a third segment of the bifurcated vessel is performed by adding a 7/3 exponent of the diameter of the first segment to a 7/3 exponent of the diameter of the second segment to obtain a 7/3 exponent of the diameter of a mother bifurcation segment, or by performing a mathematical equivalent thereof.

10. The method of claim 9, wherein the diameter of a mother bifurcation segment can be obtained by calculating a 7/3 root of the obtained 7/3 exponent of the diameter of a mother bifurcation segment.

11. The method of claim 1, wherein the bifurcated vessel is selected from the group consisting of a Y-type bifurcated vessel and a T-type bifurcated vessel.

12. The method of claim 1, wherein the steps of identifying a diameter of a first segment of a bifurcated vessel and identifying a diameter of a second segment of the bifurcated vessel are performed using coronary angiography.

13. A computer program for instructing a computer to perform the determining step of claim 1.

14. A system for determining a diameter of a segment of a bifurcated vessel, comprising:

a processor;

a storage medium operably connected to the processor, the storage medium capable of receiving and storing data indicative of measurements from a segment of a bifurcated vessel;

wherein the processor is operable to determine a diameter of a third segment of a bifurcated vessel based upon a diameter of a first segment of the bifurcated vessel and a diameter of a second segment of the bifurcated vessel based upon an exponential relationship of or about 7/3 for each diameter.

15. The system of claim 14, further comprising:

a user interface capable of receiving data indicative of the diameter of a first segment of the bifurcated vessel and the diameter of a second segment of the bifurcated vessel from a system user; and

a display mechanism to display the determined diameter of the third segment of the bifurcated vessel.

16. The system of claim 15, wherein the processor is operable to determine the diameter of the third segment of the bifurcated vessel by executing a program stored on the storage medium, the program comprising program steps indicative of the exponential relationship of or about 7/3 for each diameter.

17. The system of claim 15, wherein the user interface comprises a graphical user interface selected from the group consisting of a website, a computer software program, and a handheld device application.

18. The system of claim 14, wherein the processor and the storage medium are contained within a device selected from the group consisting of a desktop computer, a laptop computer, a tablet computer, a portable digital assistant, and a smartphone.

19. The system of claim 14, wherein the first segment, the second segment, and the third segment are selected from the group consisting of a mother bifurcation segment, a larger daughter bifurcation segment, and a smaller daughter bifurcation segment.

20. A system for determining a diameter of a segment of a bifurcated vessel, comprising:

a processor;

a storage medium operably connected to the processor, the storage medium capable of receiving and storing data indicative of measurements from a segment of a bifurcated vessel;

a user interface capable of receiving data indicative of a diameter of a first segment of a bifurcated vessel and a diameter of a second segment of the bifurcated vessel from a system user; and

a display mechanism to display a determined diameter of a third segment of the bifurcated vessel;

wherein the processor is operable to determine the diameter of a third segment of the bifurcated vessel based upon the diameter of a first segment of the bifurcated vessel and the diameter of a second segment of the bifurcated vessel by executing program steps of a program stored on the storage medium, wherein at least one of the program steps is indicative of an exponential relationship of or about 7/3 for each diameter.