APPARATUS AND MICROCHIP FOR SORTING MICRO PARTICLES
1 Assignment
0 Petitions
Accused Products
Abstract
In one example embodiment, a micro-particle sorting apparatus includes: (a) a microchip in which a flow path through which liquid containing a micro particle flows and an orifice through which the liquid flowing through the flow path is discharged into a space outside the chip; (b) an oscillating element for transforming the liquid into a liquid drop and discharging the liquid drop at the orifice; (c) a charge means for adding an electric charge to the discharged liquid drop; (d) an optical detection means that detects an optical property of the micro particle flowing through the flow path, upstream of a liquid-delivering direction with respect to the orifice; (e) paired electrodes opposed to each other while sandwiching the moving liquid drop along a movement direction of the liquid drop discharged into the space outside the chip; and two containers that collect the liquid drop passing between the paired electrodes.
48 Citations
24 Claims
-
1-12. -12. (canceled)
-
13. A micro-particle sorting apparatus comprising:
-
a microchip in which a flow path through which liquid containing a micro particle flows and an orifice through which the liquid flowing through the flow path is discharged into a space outside the chip; an oscillating element configured to transform the liquid into a liquid drop and discharge the liquid drop at the orifice; a charge means for adding an electric charge to the discharged liquid drop; an optical detection means that detects an optical property of the micro particle flowing through the flow path, upstream of a liquid-delivering direction with respect to the orifice; paired electrodes provided so as to be opposed to each other while sandwiching the moving liquid drop therebetween along a movement direction of the liquid drop discharged into the space outside the chip; and two or more containers that collect the liquid drop passing between the paired electrodes, wherein a width of the flow path and a depth of the flow path at a location of the orifice are set to be smaller than a width of the flow path and a depth of the flow path at a location at which the optical property of the micro particle is detected by the optical detection means. - View Dependent Claims (15, 16, 17, 18)
-
-
14. A micro-particle sorting apparatus comprising:
-
a microchip in which a flow path through which liquid containing a micro particle flows and an orifice through which the liquid flowing through the flow path is discharged into a space outside the chip; an oscillating element for transforming the liquid into a liquid drop and discharging the liquid drop at the orifice; a charge means for adding an electric charge to the discharged liquid drop; an optical detection means that detects an optical property of the micro particle flowing through the flow path, upstream of a liquid-delivering direction with respect to the orifice; and paired electrodes provided so as to be opposed to each other while sandwiching the moving liquid drop therebetween along a movement direction of the liquid drop discharged into the space outside the chip; and
two or more containers that collect the liquid drop passing between the paired electrodes,wherein a cross-section area of the flow path at a location of the orifice is set to be smaller than a cross-section area of the flow path at a location at which the optical property of the micro particle is detected by the optical detection means.
-
-
19. A microchip comprising:
-
a flow path through which liquid containing a micro particle flows and an orifice through which the liquid flowing through the flow path is discharged into a space outside the chip; a predetermined location of the flow path configured as a light-irradiated portion to be irradiated with light from an optical detection means for detecting an optical property of the micro particle flowing therethrough; and a micro tube that introduces, into a laminar flow of liquid T flowing through the flow path, a laminar flow of another liquid S containing micro particle, upstream of the liquid-delivering direction with respect to the light-irradiated portion, wherein a width of the flow path and a depth of the flow path at a location of the orifice are set to be smaller than a width of the flow path and a depth of the flow path at the light-irradiated portion. - View Dependent Claims (21, 22, 23, 24)
-
-
20. A microchip comprising:
-
a flow path through which liquid containing a micro particle flows and an orifice through which the liquid flowing through, the flow path is discharged into a space outside the chip; a predetermined location of the flow path configured as a light-irradiated portion to be irradiated with light from an optical detection means for detecting an optical property of the micro particle flowing therethrough; and a micro tube that introduces, into a laminar flow of liquid T flowing through the flow path, a laminar flow of another liquid S containing micro particle, upstream of the liquid-delivering direction with respect to the light-irradiated portion, wherein a cross-section area of the flow path at a location of the orifice is set to be smaller than a cross-section area of the flow path at the light-irradiated portion.
-
Specification