HYDROGEL IMPLANTS WITH VARYING DEGREES OF CROSSLINKING
First Claim
Patent Images
1. A hydrogel composition comprising:
- a first reactive precursor comprising a multi-arm polyether possessing electrophilic groups;
a second reactive precursor comprising nucleophilic groups; and
at least one initiated precursor comprising at least one vinyl group.
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Abstract
The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
17 Citations
30 Claims
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1. A hydrogel composition comprising:
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a first reactive precursor comprising a multi-arm polyether possessing electrophilic groups; a second reactive precursor comprising nucleophilic groups; and at least one initiated precursor comprising at least one vinyl group. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method comprising:
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contacting a first reactive precursor with a second reactive precursor and an initiated precursor comprising at least one vinyl group; crosslinking the first reactive precursor and the second reactive precursor to form a first hydrogel; and exposing the initiated precursor to an initiator to initiate crosslinking of the initiated precursor. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification