SYSTEMS AND METHODS FOR GASTRIC VOLUME REGULATION
First Claim
1. A method for modifying the volume of a stomach, the method comprising:
- a. creating a reduced gastric volume passageway through a portion of a stomach through which food can pass; and
b. preventing ghrelin cells within a greater curvature portion of said stomach from contacting said food.
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Accused Products
Abstract
Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.
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Citations
20 Claims
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1. A method for modifying the volume of a stomach, the method comprising:
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a. creating a reduced gastric volume passageway through a portion of a stomach through which food can pass; and b. preventing ghrelin cells within a greater curvature portion of said stomach from contacting said food. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method of regulating the activation of ghrelin hormone within a stomach of a patient, the method comprising modifying ghrelin octanoyl acyl transferase access to ghrelin within the stomach, wherein the act of modifying ghrelin octanoyl acyl transferase access to ghrelin within the stomach comprises creating a fundal wrap;
- wherein said method results in an effect selected from treatment of weight disorders, promotion of learning and/or memory functions, treatment of stress-induced depression, promotion of healthy sleep, and combinations thereof.
- View Dependent Claims (17, 18, 19)
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20. A method of regulating gastric volume, the method comprising the steps of
a. performing a full or partial fundoplication procedure in a patient, wherein the act of performing a full or partial fundoplication procedure comprises attaching one end of a fundus in said patient to an esophagus in said patient; - and
b. implanting a volume occupying device external to or within said fundus of said patient concurrent with said fundoplication procedure, such that said volume occupying device is capable of expanding or contracting based on environmental changes in said stomach.
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Specification