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THERAPEUTIC APPARATUS FOR TREATING A SUBJECT USING MAGNETIC NANOPARTICLES

  • US 20110306870A1
  • Filed: 02/22/2010
  • Published: 12/15/2011
  • Est. Priority Date: 02/27/2009
  • Status: Active Grant
First Claim
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1. A therapeutic apparatus for treating a subject (100, 200) comprising:

  • a first heating means (104, 204, 506, 606, 706) adapted for heating a first region (106, 206) of the subject,a first control means (108) for controlling the power directed into the first region by the first heating means such that the power stays below a threshold value,a particle heating means (110, 230, 232, 234, 236,238, 512, 612, 712) adapted for heating magnetic nanoparticles (114) within a second region (112,212) of the subject using a time varying magnetic field,wherein the first region comprises the second region, wherein the first heating means is an ultrasonic heating means, wherein the threshold value is selected such that the temperature increase in the first region due to the ultrasonic heating means does not induce cell death, wherein the second region comprises at least one hyperthermia zone, wherein the at least one hyperthermia zone has a concentration of magnetic nanoparticles sufficient to cause a temperature increase which induces cell death when heated by the particle heating means, and wherein the ultrasonic heating means is a high intensity focused ultrasound unit (204, 506, 606, 706).

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