Intragastric Device for Treating Obesity

• US 20110307075A1
• Filed: 06/13/2010
• Published: 12/15/2011
• Est. Priority Date: 06/13/2010
• Status: Active Grant

• Current Assignee: SynerZ Medical, Inc.
• Original Assignee: SynerZ Medical, Inc.
• Inventors: Sharma, Virender K.
• Granted Patent: US 8,628,554 B2
• Time in Patent Office: Days
• US Class Current: 623/23.65
• CPC Class Codes: A61F 2002/045 Stomach, intestines
• CPC Class Codes: A61F 2002/9155 Adjacent bands being connected to each other
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0071 spherical
• CPC Class Codes: A61F 5/0013 Implantable devices or invasive measures
• CPC Class Codes: A61F 5/0036 Intragastrical devices
• CPC Class Codes: A61F 5/0089 Instruments for placement or removal

Abstract

The present invention is directed toward an intragastric device used to treat obesity that includes a wire mesh structure capable of changing from a compressed pre-deployment shape to an expanded post-deployment shape with a greatly increased volume. The post-deployment shape contains a light weight at the top and a heavier weight at the bottom to ensure proper positioning within the stomach. In the post-deployment shape, the device contains larger spaces in the upper portion and smaller spaces in the lower portion to sequester food and delay gastric emptying. Alternatively, the device can be enveloped by a membrane containing larger holes at the top and smaller holes at the bottom to sequester food and delay gastric emptying. The device has a dynamic weight where the weight of the device in the pre-feeding stage is less than the weight of the device in feeding or post-feeding stage.

Claims

1. An intragastric device having a top and a bottom comprising:

a structure having a pre-deployment shape with a first volume and a post-deployment shape with a second volume, wherein said first volume is less than said second volume;

wherein, in said post-deployment shape, said device comprises at least one first opening proximate to the top of said device, each first opening defined by an area where a sum of the areas of the first openings is equal to a first area;

wherein, in said post-deployment shape, said device comprises at least one second opening proximate to the bottom of said device, each second opening defined by an area where a sum of the areas of the second openings is equal to a second area; and

wherein said first area is equal or larger than said second area.

2. The intragastric device of claim 1, wherein said pre-deployment shape is at least one of linear, cylindrical, or conical.

3. The intragastric device of claim 1, wherein said post-deployment shape is at least one of an expanded cylinder, ovoid, sphere, cube or cuboid.

4. The intragastric device of claim 1 where the structure comprises at least one of a wire mesh structure, a spiral structure, or a lattice structure.

5. The intragastric device of claim 4, wherein said wire mesh has a plurality of vertical and horizontal elements which, when expanded, create the at least one first opening and the at least one second opening.

6. The intragastric device of claim 5 wherein said wire mesh vertical and horizontal elements comprise at least one of a metal, an alloy, a polymer, a shape memory metal, or a shape memory polymer.

7. The intragastric device of claim 1, wherein said structure in enveloped by a partially perforated membrane having a surface area.

8. The intragastric device of claim 7, wherein said membrane comprises at least one of latex, parylene, polyurethane, polytetrafluoroethylene [PTFE], fluorinated ethylene-propylene, Dacron, or Polyethylene terephthalate (PET).

9. The intragastric device of claim 8, wherein said membrane has at least one first membrane opening, each first membrane opening having a first membrane opening area where a sum of said first membrane opening areas is equal to a third area, wherein said at least one first membrane opening is proximate to the top of the device.

10. The intragastric device of claim 9, wherein said membrane has at least one second membrane opening, each second membrane opening having a second membrane opening area where a sum of said second membrane opening areas is equal to a fourth area, wherein said at least one second membrane opening is proximate to the bottom of the device and wherein the third area is equal or larger than the fourth area.

11. The intragastric device of claim 10 wherein a sum of said third area and fourth area is between one and ninety-nine percent of the membrane surface area.

12. The intragastric device of claim 7 where said membrane comprises at least one opening and wherein said opening has at least one valve that controls a directionality of flow of food or nutrients in and out of the device.

13. The intragastric device of claim 1, wherein said device is attached to a catheter, wherein said catheter is configured to induce a change from the pre-deployment shape to said post-deployment shape.

14. The intragastric device of claim 1, wherein a sleeve is attached to the bottom of said device, wherein said sleeve has a length sufficient to extend from the bottom of the device, through a patient'"'"'s pylorus and duodenum, and into the patient'"'"'s jejunum.

15. The intragastric device of claim 14, wherein said sleeve comprises at least one of latex, parylene, polyurethane, polytetrafluoroethylene [PTFE], fluorinated ethylene-propylene, Dacron, or Polyethylene terephthalate (PET).

16. The intragastric device of claim 1, wherein said device is configured to receive a second intragastric device.

17. An intragastric device having a top and a bottom comprising:

a structure having a pre-deployment shape with a first volume and a post-deployment shape with a second volume, wherein said first volume is less than said second volume;

wherein, in said post-deployment shape, said device comprises a plurality of first openings, each of said plurality of first openings defined by an area where a sum of the areas of the plurality of first openings is equal to a first area;

wherein, in said post-deployment shape, said device comprises a plurality of second openings, each of said plurality of second openings defined by an area where a sum of the areas of the plurality of second openings is equal to a second area;

wherein said first area is equal to larger than said second area;

wherein said first area is closer to the top of device relative to the second area; and

wherein said structure is enveloped by a membrane that does not cover said first area or said second area.

18. An intragastric device having a top and a bottom comprising:

a structure having a pre-deployment shape with a first volume and a post-deployment shape with a second volume, wherein said first volume is less than said second volume;

wherein, in said post-deployment shape, said device comprises at least one first opening to allow for entry of food into the device and at least one second opening to allow for exit of food from the device, wherein the device has a first weight when a patient is in a pre-feeding stage and a second weight when a patient is in a feeding or a post-feeding stage, and wherein the second weight is greater than the first weight.

19. The device of claim 18 wherein the first opening is the same as the second opening or different from the second opening.

20. The device of claim 18 wherein the device has a top half with a first weight and a bottom half with a second weight and wherein the first weight is different from the second weight.