SYSTEM AND METHOD FOR HUMAN ANATOMIC MAPPING AND POSITIONING AND THERAPY TARGETING

• US 20110313479A1
• Filed: 06/22/2010
• Published: 12/22/2011
• Est. Priority Date: 06/22/2010
• Status: Abandoned Application

• Current Assignee: Philip Rubin
• Original Assignee: Philip Rubin
• Inventors: Rubin, Philip
• Application Number:
  US12/820,598
• Publication Number:
  US 20110313479A1
• Time in Patent Office: Days
• US Class Current: 607/1
• CPC Class Codes: A61B 6/12 Arrangements for detecting or locating foreign bodies
• CPC Class Codes: A61B 6/504 for diagnosis of blood vessels, e.g. by angiography
• CPC Class Codes: A61B 6/5229 combining image data of a patient, e.g. combining a functional image with an anatomical image
• CPC Class Codes: A61B 6/5235 combining images from the same or different ionising radiation imaging techniques, e.g. PET and CT
• CPC Class Codes: A61B 6/5247 combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
• CPC Class Codes: A61N 5/103 Treatment planning systems
• CPC Class Codes: G06T 15/50 Lighting effects
• CPC Class Codes: G06T 19/00 Manipulating 3D models or images for computer graphics
• CPC Class Codes: G06T 2210/41 Medical
• CPC Class Codes: G06T 2210/44 Morphing
• CPC Class Codes: G06T 2219/028 Multiple view windows (top-side-front-sagittal-orthogonal)
• CPC Class Codes: G06T 3/14 Transformations for image registration, e.g. adjusting or mapping for alignment of images

Abstract

A method of image processing, comprising obtaining a three-dimensional standard animal body image having three intersecting two-dimensional planes and comprising an anatomical landmark; obtaining a three-dimensional radiographic image of a patient animal having a corresponding anatomical landmark; and comparing the standard animal body image with the radiographic image by: identifying the location of the anatomical landmark on one two-dimensional plane in the standard animal body image; automatically propagating the identified location of the anatomical landmark to the other two two-dimensional planes in the standard animal body image; identifying the location of the anatomical landmark in the radiographic image of the patient animal; and morphing the radiographic image of the patient animal to the standard animal body image by deforming the radiographic image of the patient animal to cause the locations of the landmark on the radiographic image and the standard animal body image to overlap.

Claims

1. A method, comprising:

obtaining a three-dimensional standard animal body image having three intersecting two-dimensional planes and comprising an anatomical landmark;

obtaining a three-dimensional radiographic image of a patient animal having a corresponding anatomical landmark; and

comparing the standard animal body image with the radiographic image by;

identifying the location of the anatomical landmark on one two-dimensional plane in the standard animal body image;

automatically propagating the identified location of the anatomical landmark to the other two two-dimensional planes in the standard animal body image;

identifying the location of the anatomical landmark in the radiographic image of the patient animal; and

morphing the radiographic image of the patient animal to the standard animal body image by deforming the radiographic image of the patient animal to cause the locations of the landmark on the radiographic image and the standard animal body image to overlap.

2. The method of claim 1, wherein said anatomical landmark is an organ that is cancerous in the patient animal.

3. The method of claim 1, wherein said anatomical landmark is an organ that has been subjected to radiation therapy.

4. The method of claim 1, wherein said standard animal body image includes a vasculature tree.

5. The method of claim 4, further comprising:

identifying, in the radiographic image of the patient animal, portions of said vasculature tree feeding into the location of the anatomical landmark.

6. The method of claim 4, further comprising:

quantifying a blood input characteristic of the anatomical landmark based on the identified portions of said vascular tree.

7. The method of claim 4, wherein the vasculature tree further comprise a plurality of lymph nodes.

8. The method of claim 7, further comprising:

classifying the radiographic image on an oncology index according to the location of the plurality of lymph nodes relative to the anatomical landmark.

9. The method of claim 7, further comprising:

determining if at least one of the plurality of lymph nodes is cancerous.

10. The method of claim 1, further comprising:

color coding the morphed radiographic image, wherein said color coding corresponds to one of a desired radiation dose for treating the anatomical landmark, a tolerance level to an ionizing radiation, or a metastasis index.

11. The method of claim 10, further comprising:

planning a radiation treatment based on the color coding.

12. The method of claim 11, wherein said treatment is one of an external beam radiation, a radioisotope therapy, an ultrasound therapy, a microwave therapy, or combinations thereof.

13. The method of claim 12, further comprising:

prognosing a medical condition based on the color coding.

14. A computer-readable medium, containing software, which software, when executed by a computer, causes the computer to execute the method of claim 1.

19. A computer-readable medium, containing software, which software, when executed by a computer, causes the computer to execute the method of claim 14.

15. A method for processing radiographic images, comprising:

obtaining a three-dimensional standard animal body image having three intersecting two-dimensional planes, wherein said three-dimensional standard animal body image includes a vasculature tree;

obtaining a three-dimensional radiographic image of a patient body;

comparing the standard animal body image and the radiographic image of the patient body by;

identifying the location of an anatomical landmark in the standard animal body image and the radiographic image of the patient body;

morphing the radiographic image of the patient body to the standard animal body image by deforming the radiographic image to cause the locations of the anatomical landmark on the radiographic image of the patient body and the standard animal body image to overlap;

fusing the radiographic image of the patient body and the standard animal body image to produce a three dimensional representation of the identified anatomical landmark; and

visualizing the vasculature tree relative to the corresponding location of the identified anatomical landmark on the fused image.

16. The method of claim 15, wherein the vasculature tree further comprises a plurality of lymph nodes.

17. The method of claim 16, further comprising:

classifying the fused image on an oncology index according to the location of the plurality of lymph nodes relative to the anatomical landmark.

18. The method of claim 15, further comprising:

color coding the fused image, wherein said color coding corresponds to one of a desired radiation dose for treating the medically relevant organ, a tolerance level to an ionizing radiation, or a metastasis index.

20. A system for viewing multi-dimensional images of an animal body, comprising:

a computer system comprising;

a storage device having a three-dimensional radiographic image of a patient body and a standard animal body image, wherein the radiographic image of the patient body has data corresponding to each plane of the standard animal body image, and the standard animal body image comprises a vasculature tree;

a processor, in communication with the storage device, to identify an anatomical landmark in both the three-dimensional standard image body and the radiographic image of the patient body, identify the locations of the anatomical landmark in the standard animal body image and the radiographic image of the patient body, morph the radiographic image of the patient body to the standard animal body image by deforming the radiographic image to cause the locations of the landmark on the radiographic image of the patient body and the standard animal body image to overlap, and to fuse radiographic image of the patient body and the standard animal body image to produce a three dimensional representation of the identified anatomical landmark; and

a display device, in communication with the processor and the storage device, to visualize the vasculature tree relative to the corresponding location of the identified anatomical landmark on the fused image.

21. The system of claim 20, further comprising:

a radiation delivery system to deliver a radiation energy to the patient body, wherein

the therapy system is in communication with the computer system to receive treatment information corresponding to the radiographic image fused with the standard animal body image, and

the radiation energy is one of a X-ray energy, a α

-ray energy, β

-ray energy, a γ

-ray energy, a microwave energy, an ultrasound energy, or combinations thereof.

22. The system of claim 20, wherein

the vasculature tree further comprises surrounding lymph nodes.