NASAL DELIVERY
First Claim
1. Nasal administration of angiotensin antagonists, angiotensin (AT) II receptor antagonists (angiotensin receptor blockers), AT1 receptor antagonists and sartans, such as losartan, angiotensin-converting enzyme (ACE) inhibitors, glycine receptor antagonists, anti-histamines, in particular non-selective antihistamines, such as dimebon (2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl 3-pyridinypethyl]-1H-pyrido[4,3-b]indole provided as the dichloride salt), morphine, glycogen synthase kinase 3 (GSK3) inhibitors, such as substituted pyrazolo[3,4-b]pyridin-6-ones, substituted 4-amino[1,2,4]triazolo[4,3-a]quinoxalines, pyrimidine and pyridine derivatives and lithium, tumor necrosis factor (TNF) blockers, such as etanercept, infliximab and adalimumab, oxytocin, or cells, including stern cells and glioma cells, for the treatment of neurological diseases and conditions, including neurodegenerative diseases and conditions, such as Alzheimer'"'"'s disease, Huntington'"'"'s disease, Parkinson'"'"'s disease, dementia and stroke, bi-polar disorder, diabetes, schizophrenia, depression, anxiety, hair loss, cancer, obesity, atherosclerotic cardiovascular disease, essential hypertension, polycystic ovary syndrome, syndrome X, ischemia, especially cerebral ischemia, traumatic brain injury, immunodeficiency, autism, sexual dysfunction, regulation of maternal behaviour, regulation of female sexual behaviour, regulation of male sexual behaviour, regulation of social behaviour, including regulation of male and female aggression, promoting social memory, including social recognition and pair bonding, promoting learning, promoting memory, suppression of fever, or by way of pain relief, such as in the treatment of breakthrough pain.
1 Assignment
0 Petitions
Accused Products
Abstract
substances and the nasal administration thereof, in particular as one of a liquid, as a suspension or solution, or a powder, to the nasal airway of a subject, in particular the posterior region of the nasal airway, and in particular the upper posterior region of the nasal airway, which includes the olfactory bulb, in particular in the treatment of neurological conditions and disorders.
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Citations
17 Claims
- 1. Nasal administration of angiotensin antagonists, angiotensin (AT) II receptor antagonists (angiotensin receptor blockers), AT1 receptor antagonists and sartans, such as losartan, angiotensin-converting enzyme (ACE) inhibitors, glycine receptor antagonists, anti-histamines, in particular non-selective antihistamines, such as dimebon (2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl 3-pyridinypethyl]-1H-pyrido[4,3-b]indole provided as the dichloride salt), morphine, glycogen synthase kinase 3 (GSK3) inhibitors, such as substituted pyrazolo[3,4-b]pyridin-6-ones, substituted 4-amino[1,2,4]triazolo[4,3-a]quinoxalines, pyrimidine and pyridine derivatives and lithium, tumor necrosis factor (TNF) blockers, such as etanercept, infliximab and adalimumab, oxytocin, or cells, including stern cells and glioma cells, for the treatment of neurological diseases and conditions, including neurodegenerative diseases and conditions, such as Alzheimer'"'"'s disease, Huntington'"'"'s disease, Parkinson'"'"'s disease, dementia and stroke, bi-polar disorder, diabetes, schizophrenia, depression, anxiety, hair loss, cancer, obesity, atherosclerotic cardiovascular disease, essential hypertension, polycystic ovary syndrome, syndrome X, ischemia, especially cerebral ischemia, traumatic brain injury, immunodeficiency, autism, sexual dysfunction, regulation of maternal behaviour, regulation of female sexual behaviour, regulation of male sexual behaviour, regulation of social behaviour, including regulation of male and female aggression, promoting social memory, including social recognition and pair bonding, promoting learning, promoting memory, suppression of fever, or by way of pain relief, such as in the treatment of breakthrough pain.
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17. Angiotensin antagonists, anglotensin (AT) H receptor antagonists (angiotensin receptor blockers), AT1 receptor antagonists and sartans, such as losartan, angiotensin-converting enzyme (ACE) inhibitors, glycine receptor antagonists, anti-histamines, in particular non-selective antihistamines, such as dimebon (2,3,4,5-tetra hydro-2,8-dimethyl-5-[2-(6-methyl 3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indole provided as the dichloride salt), morphine, glycogen synthase kinase 3 (GSK3) inhibitors, such as substituted pyrazolo[3,4-b]pyridin-6-ones, substituted 4-amino[1,2,4]triazolo[4,3-a]quinoxalines, pyrimidine and pyridine derivatives and lithium, tumor necrosis factor (TNF) blockers, such as etanercept, infliximab and adalimumab, oxytocin, or cells, including stem cells and glioma cells, for the treatment of neurological diseases and conditions, including neurodegenerative diseases and conditions, such as Alzheimer'"'"'s disease, Huntington'"'"'s disease, Parkinson'"'"'s disease, dementia and stroke, bi-polar disorder, diabetes, schizophrenia, depression, anxiety, hair loss, cancer, obesity, atherosclerotic cardiovascular disease, essential hypertension, polycystic ovary syndrome, syndrome X, ischemia, especially cerebral ischemia, traumatic brain injury, immunodeficiency, autism, sexual dysfunction, regulation of maternal behaviour, regulation of female sexual behaviour, regulation of male sexual behaviour, regulation of social behaviour, including regulation of male and female aggression, promoting social memory, including social recognition and pair bonding, promoting learning, promoting memory, suppression of fever, or by way of pain relief, such as in the treatment of breakthrough pain.
Specification