METHODS AND SYSTEMS FOR MONITORING INTRABODY TISSUES

• US 20110319746A1
• Filed: 03/04/2010
• Published: 12/29/2011
• Est. Priority Date: 09/05/2007
• Status: Active Grant

• Current Assignee: Sensible Medical Innovations Ltd.
• Original Assignee: Sensible Medical Innovations Ltd.
• Inventors: Kochba, Ilan, Rappaport, Dan, Saroka, Amir, Bergida, Shlomi, Mizrahi, Nadav, Ronen, Amir
• Granted Patent: US 9,572,511 B2
• Time in Patent Office: Days
• US Class Current: 600/407
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/0507 using microwaves or terahertz waves
• CPC Class Codes: A61B 5/4076 Diagnosing or monitoring particular conditions of the nervous system A61B5/4821, A61B5/4824 take precedence
• CPC Class Codes: A61B 5/412 Detecting or monitoring sepsis
• CPC Class Codes: A61B 5/4504 Bones A61B5/4547 takes precedence
• CPC Class Codes: A61B 5/4842 Monitoring progression or stage of a disease
• CPC Class Codes: A61B 5/4848 Monitoring or testing the effects of treatment, e.g. of medication
• CPC Class Codes: A61B 5/4869 Determining body composition
• CPC Class Codes: A61B 5/72 Signal processing specially adapted for physiological signals or for diagnostic purposes character recognition, recognising digital ink, document-oriented image-based pattern recognition G06V30/00; recognition or understanding of postal images G06V30/424
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence

Abstract

A method for monitoring an intrabody region of a patient. The method comprises intercepting electromagnetic (EM) radiation from the intrabody region in a plurality of EM radiation sessions during a period of at least 6 hours, calculating a dielectric related change of the intrabody region by analyzing respective the intercepted EM radiation, detecting a physiological pattern according to said dielectric related change, and outputting a notification indicating the physiological pattern.

Claims

1. A method for monitoring an intrabody region of a patient, comprising:

intercepting electromagnetic (EM) radiation from the intrabody region in a plurality of EM radiation sessions during a period of at least 6 hours;

calculating a dielectric related change of the intrabody region by analyzing respective said intercepted EM radiation;

detecting a physiological pattern according to said dielectric related change; and

outputting a notification indicating said physiological pattern.

2. The method of claim 1, wherein the patient is an ambulatory patient and said intercepting being performed during a period of at least 12 hours.

3. The method of claim 1, wherein said dielectric related change reflects a change in a plurality of properties of said intrabody region.

4. The method of claim 3, wherein said plurality of properties comprises a member of a group consisting of a density, a size, a shape, and a concentration of fluids.

5. The method of claim 1, wherein said calculating comprising registering EM radiations intercepted during a first of said plurality of EM radiation sessions with a second of said plurality of EM radiation sessions.

6. The method of claim 1, wherein the intrabody region comprises a cancerous tissue and said physiological pattern is a reaction of said cancerous tissue to an oncological therapy.

7. The method of claim 6, wherein said physiological pattern is a reaction of said cancerous tissue to a member selected from a group consisting of:

a chemotherapy cycle, a biologic treatment and a radiation treatment.

8. The method of claim 1, wherein said physiological pattern is a reaction of said intrabody region to a medical operation performed on said patient.

9. The method of claim 1, further comprising automatically dispensing a medical substance into said patient according to said physiological pattern.

10. The method of claim 1, wherein said notification comprises a recommendation to a medical procedure according to said physiological pattern.

11. The method of claim 10, wherein said medical procedure comprising a member of a group consisting of:

a dosage of a medical agent, a dispensing of a medical substance, a radiation protocol, a rehabilitation process, and a diagnosis procedure.

12. The method of claim 1, wherein said detecting is performed by combining at least one biological parameter of said patient with said dielectric related change.

13. The method of claim 12, wherein said at least one biological parameter comprises a member of a group consisting of:

an electrocardiogram (ECG) signal, a temperature, a body orientation, a body acceleration, a hemodynamic parameter, CO₂ saturation, O₂ saturation, a pulse wave and a blood pressure.

14. The method of claim 1, wherein said detecting is performed by combining at least one diagnostic result related to said intrabody region with said dielectric related change for detecting said physiological pattern.

15. The method of claim 1, wherein said intrabody region is a pulmonary tissue and said notification is indicative of atelectasis.

16. The method of claim 1, wherein said physiological pattern is an expected dielectric related change indicative of a blood accumulation in an intrabody tissue.

17. The method of claim 1, wherein said intrabody region comprises a cerebral tissue and said physiological pattern is indicative of a cerebral edema.

18. The method of claim 1, wherein the patient is a non compliant patient selected from a group consisting of an intensive care patient, a newborn suffering from respiratory distress syndrome, a patient under anesthesia, an unconscious patient, an injured patient, a child patient and a toddler patient.

20. The method of claim 1, further comprising using an imaging modality for detecting at least one characteristic of said intrabody tissue, said detecting is performed according to said at least one characteristic.

21. The method of claim 1, wherein said physiological pattern is based on a reference parameter extracted from a modality imaging said intrabody region.

22. The method of claim 1, wherein said patient is an intubated patient and said intrabody region comprises a pulmonary tissue.

29. The method of claim 1 further comprising

fixating a monitoring device in relation to a body of a non-compliant patient;

wherein said intercepting, said calculating, said detecting, and said outputting is performed by said monitoring device.

30. The method of claim 29, wherein said intercepting is performed while said patient being transported.

32. The method of claim 1 wherein said calculating comprises combining two narrowband signals from said EM radiation.

33. The method of claim 1, wherein said monitoring device is wearable.

34. The method of claim 1, wherein said intercepted EM radiation passes through the intrabody region.

19. (canceled)

23. (canceled)

24. A method for monitoring an intrabody region, comprising:

performing stress ergometry on a patient according to a stress examination test;

intercepting electromagnetic (EM) radiation from the at least one intrabody region of said patient in at least one EM radiation session;

calculating a dielectric related change of the at least one intrabody region by analyzing respective said intercepted EM radiation;

detecting a physiological pattern according to said dielectric related change; and

outputting a notification indicating said physiological pattern.

25. A monitoring device for detecting a physiological pattern of an intrabody region, comprising:

at least one probe configured for intercepting electromagnetic (EM) radiation from the intrabody region of a patient;

a processing unit configured for calculating a dielectric related change of the intrabody region by analyzing respective said intercepted EM radiation_and detecting a physiological pattern according to said dielectric related change; and

an output unit configured for outputting a message indicating said physiological pattern;

wherein said probe and said processing unit are configured for respectively performing said intercepting and said analyzing in a plurality of EM radiation sessions during a period of at least 6 hours.

26. The monitoring device of claim 25, wherein said output unit is connected to a medical device providing a treatment to said patient, said medical device being configured for providing said treatment according to said message.

27. The monitoring device of claim 26, wherein said medical device comprises a respiration machine being configured to apply artificial respiration to said patient, said respiration machine being configured for adjusting said artificial respiration according to said message.

31. The monitoring device of claim 25 wherein said at least one probe is configured for intercepting said electromagnetic (EM) radiation from a reference intrabody region of said patient;

and wherein said processing unit is configured for calculating a dielectric related change in said intrabody region and a reference dielectric related change in said reference intrabody region according to said intercepted EM radiation and identifying a physiological pattern according to a combination of said dielectric related change and reference dielectric related change.

28. (canceled)

35. A monitoring device for detecting a physiological pattern of an intrabody region, comprising:

at least one first probe which transmits electromagnetic (EM) radiation toward the intrabody region of a patient in a plurality of EM radiation sessions during a period of at least 6 hours;

at least one second probe which intercepts at least a portion of said EM radiation in each said EM radiation session, said portion passing through said intrabody region;

a processing unit which calculates a dielectric related change of the intrabody region by analyzing respective said portion in said plurality of EM radiation sessions and detecting a physiological pattern according to said analysis; and

an output unit which outputs a message indicating said physiological pattern.