REDUCING FLOW THROUGH A TUBULAR STRUCTURE

• US 20110319906A1
• Filed: 06/29/2010
• Published: 12/29/2011
• Est. Priority Date: 06/29/2010
• Status: Active Grant

• Current Assignee: ArtVentive Medical Group Inc
• Original Assignee: ArtVentive Medical Group Inc
• Inventors: RUDAKOV, Leon, GAILLOUD, Phillipe
• Granted Patent: US 9,017,351 B2
• Time in Patent Office: Days
• US Class Current: 606/127
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/1204 temporary occlusion
• CPC Class Codes: A61B 17/12104 in an air passage
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 2017/00469 for insertion of instruments, e.g. guide wire, optical fibre
• CPC Class Codes: A61B 2017/00809 Lung operations
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/1209 detachable by electrical current or potential, e.g. electroactive polymer
• CPC Class Codes: A61B 2017/22035 for retrieving or repositioning foreign objects

Abstract

In some embodiments, an apparatus, for reducing or stopping flow through a tubular structure of a patient, includes an elongate member arranged to form a frame having a distal and proximal opening and configured to be positioned within a lumen of the tubular structure. The frame includes a proximal, distal, and middle portion. The distal portion is tapered such that an outer cross sectional dimension (OCSD) of the distal opening is less than an OCSD of the middle portion. The frame is configured to be inverted such that the distal portion moves within and toward the middle portion for removing the frame from within the lumen. The apparatus also comprises a flow reducing member coupled to the frame such that when the frame is positioned within the lumen, the flow reducing member substantially reduces or totally obstructs flow of at least one of emboli and fluid flowing through the lumen.

Claims

1. An apparatus for reducing or stopping flow through a tubular structure of a patient, the apparatus comprising:

a first elongate member arranged to form a first frame having a distal opening and a proximal opening, the first frame configured to be positioned within a lumen of the tubular structure, the first frame having a proximal portion, a distal portion, and a middle portion therebetween, the distal portion tapered such that an outer cross sectional dimension of the distal opening is less than an outer cross sectional dimension of the middle portion, the first frame configured to be inverted such that the distal portion moves within and toward the middle portion for removing the first frame from within the lumen; and

a first flow reducing member coupled to the first frame such that when the first frame is positioned within the lumen, the first flow reducing member substantially reduces or totally obstructs flow of at least one of emboli and fluid flowing through the lumen.

2. The apparatus of claim 1, wherein the first elongate member is arranged in a spiral configuration to form the first frame.

3. The apparatus of claim 1, wherein the proximal portion is tapered such that an outer cross sectional dimension of the proximal opening is less than the outer cross sectional dimension of the middle portion.

4. The apparatus of claim 1, wherein the first elongate member comprises a substantially rectangular cross section.

5. The apparatus of claim 1, wherein the first flow reducing member comprises a plurality of pores each having a diameter of between about 5 microns and about 10 microns.

6. The apparatus of claim 1, wherein the first flow reducing member is disposed over an exterior of the first frame.

7. The apparatus of claim 6, wherein the first flow reducing member is disposed over the distal portion.

8. The apparatus of claim 7, wherein at least a portion of the first flow reducing member extends from the exterior of the first frame into an interior of the first frame through the distal opening to form a flap in the interior of the first frame, the flap configured to substantially prevent distal flow through the distal opening and facilitate proximal flow through the distal opening.

9. The apparatus of claim 2, wherein the first flow reducing member is disposed in an interior of the first frame.

10. The apparatus of claim 9, wherein the first flow reducing member is coupled to a first coil of the first frame such that the first flow reducing member substantially covers an opening through the first coil.

11. The apparatus of claim 10, wherein a thickness of the first coil of the first frame measured along an axial dimension of the first frame is less than a thickness of a second coil of the first frame measured along the axial dimension of the first frame.

12. The apparatus of claim 1, further comprising a retrieving member configured to couple to the distal portion and to retrieve the distal portion toward an interior of the first frame for inverting the first frame.

13. The apparatus of claim 1, further comprising:

an outer catheter configured to be positioned within the lumen at a first deployment site; and

an inner catheter disposed within the outer catheter,

wherein the first frame is configured to be positioned between the inner catheter and the outer catheter for stowage of the first frame before the first frame is deployed within the lumen.

14. The apparatus of claim 13, further comprising one or more threads formed in or on an outer surface of the inner catheter such that the first elongate member wraps around the one or more threads for securing the first elongate member to the inner catheter.

15. The apparatus of claim 13, wherein the first flow reducing member is disposed over the distal portion, wherein the distal portion and the first flow reducing member extend distally beyond a distal opening of the outer catheter such that when the outer catheter is moved within the lumen to the first deployment site, the distally extended portion of the first flow reducing member is configured to engage a wall of the lumen to reduce friction.

16. The apparatus of claim 13, further comprising a guide wire configured to extend through the inner catheter and the distal opening of the first frame.

17. The apparatus of claim 16, further comprising:

a second elongate member arranged in a spiral configuration to form a second frame having a distal opening and a proximal opening, the second frame configured to be positioned within the lumen, the second frame having a proximal portion, a distal portion, and a middle portion therebetween, the distal portion of the second frame tapered such that an outer cross sectional dimension of the distal opening of the second frame is less than an outer cross sectional dimension of the middle portion of the second frame, the second frame configured to be inverted such that the distal portion of the second frame moves within and toward the middle portion of the second frame for removing the second frame from within the lumen; and

a second flow reducing member coupled to the second frame such that when the second frame is positioned within the lumen, the second flow reducing member substantially reduces or totally obstructs flow of at least one of emboli and fluid flowing through the lumen,

wherein the second frame is configured to be positioned between the outer catheter and the guide wire for stowage of the second frame before the second frame is deployed within the lumen.

18. A method for reducing or stopping flow through a tubular structure of a patient, the method comprising:

positioning a first elongate member within a lumen of the tubular structure, the first elongate member arranged to form a first frame having a distal opening and a proximal opening, the first frame having a proximal portion, a distal portion, and a middle portion therebetween, the distal portion tapered such that an outer cross sectional dimension of the distal opening is less than an outer cross sectional dimension of the middle portion;

substantially reducing or totally obstructing, with a first flow reducing member coupled to the first frame, flow of at least one of emboli and fluid flowing through the lumen; and

removing the first frame from within the lumen by inverting the first frame such that the distal portion moves within and toward the middle portion.

19. The method of claim 18, further comprising:

extending a tube through the distal opening to position the tube at a target site of the patient; and

applying, with a vacuum source, a vacuum through the tube for removing at least one of emboli and fluid from the target site.

20. A method for reducing or stopping flow through a tubular structure of a patient, the method comprising:

positioning an outer catheter within a lumen of the tubular structure at a first deployment site, wherein an inner catheter is disposed within the outer catheter, wherein a first elongate member is positioned between the inner catheter and the outer catheter, the first elongate member arranged to form a first frame having a distal opening and a proximal opening, the first frame having a proximal portion, a distal portion, and a middle portion therebetween, the distal portion tapered such that an outer cross sectional dimension of the distal opening is less than an outer cross sectional dimension of the middle portion,

partially deploying the first frame from the outer catheter by shifting the inner catheter distally relative to the outer catheter until a portion of the first frame extends beyond a distal opening of the outer catheter into the first deployment site;

retracting the first frame into the outer catheter by shifting the inner catheter proximally relative to the outer catheter until the portion of the first frame is retracted proximally into the outer catheter;

positioning the outer catheter within the lumen at a second deployment site for deploying the first frame at the second deployment site;

deploying the first frame from the outer catheter by shifting the inner catheter distally relative to the outer catheter until the first frame extends beyond the distal opening of the outer catheter into the second deployment site; and

substantially reducing or totally obstructing, with a first flow reducing member coupled to the first frame, flow of at least one of emboli and fluid flowing through the lumen.