METHOD AND SYSTEM FOR TREATING PHOTOAGED TISSUE

• US 20120004549A1
• Filed: 09/12/2011
• Published: 01/05/2012
• Est. Priority Date: 10/06/2004
• Status: Active Grant

• Current Assignee: Guided Therapy Systems Llc
• Original Assignee: Guided Therapy Systems Llc
• Inventors: Barthe, Peter G., Slayton, Michael H., Makin, Inder Raj S.
• Granted Patent: US 8,641,622 B2
• Time in Patent Office: Days
• US Class Current: 600/439
• CPC Class Codes: A61B 2017/320069 for ablating tissue
• CPC Class Codes: A61B 5/682 Mouth, e.g., oral cavity; tongue; Lips; Teeth
• CPC Class Codes: A61B 5/6842 by marking the skin
• CPC Class Codes: A61B 8/08 Detecting organic movements or changes, e.g. tumours, cysts, swellings A61B8/02 - A61B8/06 take precedence
• CPC Class Codes: A61B 8/0858 involving measuring tissue layers, e.g. skin, interfaces
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/13 Tomography A61B8/10, A61B8/12 take precedence; tomography for radiation diagnosis A61B6/02
• CPC Class Codes: A61B 8/4209 by using holders, e.g. positioning frames
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61B 8/4455 Features of the external shape of the probe, e.g. ergonomic aspects
• CPC Class Codes: A61B 8/4483 characterised by features of the ultrasound transducer
• CPC Class Codes: A61B 8/461 Displaying means of special interest
• CPC Class Codes: A61B 8/483 involving the acquisition of a 3D volume of data
• CPC Class Codes: A61B 8/546 involving monitoring or regulation of device temperature
• CPC Class Codes: A61H 2201/5007 computer controlled
• CPC Class Codes: A61H 23/0245 with ultrasonic transducers, e.g. piezoelectric
• CPC Class Codes: A61N 2007/0008 Destruction of fat cells
• CPC Class Codes: A61N 2007/0034 Skin treatment
• CPC Class Codes: A61N 2007/0052 using the same transducer for therapy and imaging
• CPC Class Codes: A61N 2007/027 with multiple foci created simultaneously
• CPC Class Codes: A61N 7/00 : Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092
• CPC Class Codes: A61N 7/02 : Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: G01S 15/8909 : using a static transducer configuration

Abstract

A method and system for ultrasound treatment of photoaged tissue are provided. An exemplary method and system are configured for first, ultrasound imaging of the region of interest for localization of the treatment area, second, delivery of ultrasound energy at a depth and pattern to achieve the desired therapeutic effects, and third to monitor the treatment area during and after therapy to assess the results and/or provide feedback. The exemplary treatment method and system can be configured for producing arrays of sub-millimeter and larger zones of thermal ablation to treat the epidermal, superficial dermal, mid-dermal and deep dermal components of photoaged tissue.

Claims

1. A method of rejuvenating skin with a combined imaging and therapy ultrasound transducer, the method comprising:

identifying a treatment area comprising a skin surface, dermal tissue, and muscle tissue;

imaging at least a portion of the treatment area with an ultrasound transducer configured for both imaging and therapy; and

delivering ultrasound energy with the ultrasound transducer through the skin surface and into a portion of the treatment area comprising the dermal tissue and the muscle tissue to cause thermally injury to a portion of the dermal tissue and the muscle tissue, thereby rejuvenating the skin surface.

2. The method according to claim 1, wherein the delivering ultrasound energy is in a frequency range of about 2 MHz to about 25 MHz.

3. The method according to claim 1, wherein the imaging is performed in a frequency range of about 2 MHz to about 75 MHz.

4. The method according to claim 1, wherein the delivering ultrasound energy is at an energy level sufficient to raise a temperature of the portion of the dermal tissue and the muscle tissue to greater than about 60°

C.

5. The method according to claim 1, wherein the delivering ultrasound energy is at an energy level sufficient to denature tissue in the portion of the treatment area comprising the dermal tissue and the muscle tissue.

6. The method according to claim 1, wherein the delivering ultrasound energy is at an energy level sufficient to ablate the portion of the dermal tissue and the muscle tissue.

7. The method according to claim 1, wherein the delivering ultrasound energy is an energy level sufficient to cause shrinkage of tissue in the portion of the treatment area comprising the dermal tissue and the muscle tissue.

8. The method according to claim 1, wherein the rejuvenating the skin surface further comprises stimulating a healing effect in the portion of the treatment area comprising the dermal tissue and the muscle tissue.

9. The method according to claim 1, wherein the skin surface is photo damaged.

10. The method according to claim 1, wherein the skin surface comprises one or more wrinkles.

11. The method according to claim 1, wherein the rejuvenating the skin surface further comprises reducing laxity of the treatment area.

12. The method according to claim 1, wherein the delivering ultrasound energy is to a depth of about 5 mm below the skin surface.

13. A method of rejuvenating skin with a combined imaging and therapy ultrasound transducer, the method comprising:

identifying a treatment area comprising a skin surface, dermal tissue, and muscle tissue,

imaging at least a portion of the treatment area with an ultrasound transducer configured for both imaging and therapy;

delivering ultrasound energy with the ultrasound transducer through the skin surface to at least one of the dermal tissue and the muscle tissue in the treatment area to cause thermally injury to a portion of at least one of the dermal tissue and the muscle tissue in the treatment area, thereby rejuvenating the skin surface.

14. The method according to claim 13, wherein the delivering ultrasound energy further comprises causing shrinkage of tissue in the portion of at least one of the dermal tissue and the muscle tissue in the treatment area,

15. The method according to claim 13, wherein the skin surface comprises one or more wrinkles.

16. The method according to claim 13, wherein the rejuvenation of the skin surface comprises a reduction of laxity.

17. A method of rejuvenating skin, the method comprising:

identifying a portion of a treatment area comprising a skin surface, dermal tissue and muscle tissue with an ultrasound source;

delivering ultrasound energy from the ultrasound source to a first target in the treatment area at a depth below the skin surface;

moving the ultrasound source;

delivering ultrasound energy from the ultrasound source to a second target in the treatment area at the depth below the skin surface to create a plurality of conformal lesions at the depth in a portion of the dermal tissue and the muscle tissue, thereby shrinking a volume of tissue in the portion of the dermal tissue and the muscle tissue to rejuvenate the skin surface.

18. The method according to claim 17, wherein the delivering ultrasound energy further comprises stimulating a healing effect in the portion of the dermal tissue and the muscle tissue.

19. The method according to claim 17, wherein the delivering ultrasound energy further comprises ablating the portion of the dermal tissue and the muscle tissue in the treatment area.

20. The method according to claim 17, further comprising imaging the portion of the treatment area with the ultrasound source.