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Genome editing of a Rosa locus using zinc-finger nucleases

  • US 20120017290A1
  • Filed: 04/25/2011
  • Published: 01/19/2012
  • Est. Priority Date: 04/26/2010
  • Status: Active Grant
First Claim
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1. A fusion protein comprising a nuclease and an engineered zinc finger domain, wherein the engineered zinc finger domain binds to a target site specified in any of SEQ ID NOs:

  • 28-30 and 75-90.

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