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HEDGEHOG PATHWAY INHIBITORS

  • US 20120020876A1
  • Filed: 01/22/2010
  • Published: 01/26/2012
  • Est. Priority Date: 01/23/2009
  • Status: Abandoned Application
First Claim
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1. A method of:

  • increasing delivery of an agent to a tissue, or treating or preventing tumor metastasis in a mammal, comprising administering a hedgehog pathway inhibitor and said agent to said tissue;

    increasing blood density in a tissue, reducing stromal content in a tissue, increasing blood vessel patency in a tissue, or promoting angiogenesis in a tissue, comprising administering a hedgehog pathway inhibitor to said tissue;

    orimaging a tissue, comprising the steps of administering a hedgehog inhibitor to said tissue and using an imaging technique to image said tissue;

    orimaging a tissue comprises the steps of administering a hedgehog pathway inhibitor and an imaging agent to said tissue and using an imaging technique to image said tissue.

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