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METHODS OF ENHANCING T CELL RESPONSIVENESS

  • US 20120027759A1
  • Filed: 07/13/2010
  • Published: 02/02/2012
  • Est. Priority Date: 04/20/2001
  • Status: Abandoned Application
First Claim
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1. A method of enhancing T cell responsiveness in a mammal, the method comprising:

  • (a) identifying a mammal with, or at risk of developing, cancer, wherein the cells of the cancer are identified as expressing B7-H1 molecules on their surfaces; and

    (b) administering to the subject a compound comprising an agent that interferes with an interaction between B7-H1 and a T cell.

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