SLIP CHIP DEVICE AND METHODS
First Claim
1. A device for carrying out a reaction, the device comprising:
- a first part having a first surface;
at least one first area located along a portion of the first surface, the at least one first area configured to maintain at least one first substance;
a second part having a second surface opposed to the first surface; and
at least one second area located along a portion of the second surface, the at least one second area configured to maintain at least one second substance, wherein at least one of the first surface of the first part and the second surface of the second part is configured to move relative to the other between a first position, where the at least one first area is not exposed to the at least one second area, and a second position, where one of the at least one first areas is only exposed to one of the at least one second areas and form a closed system.
2 Assignments
0 Petitions
Accused Products
Abstract
A device is described having a first surface having a plurality of first areas and a second surface having a plurality of second areas. The first surface and the second surface are opposed to one another and can move relative to each other from at least a first position where none of the plurality of first areas, having a first substance, are exposed to plurality of second areas, having a second substance, to a second position. When in the second position, the plurality of first and second areas, and therefore the first and second substances, are exposed to one another. The device may further include a series of ducts in communication with a plurality of first second areas to allow for a substance to be disposed in, or upon, the plurality of second areas when in the first position.
148 Citations
28 Claims
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1. A device for carrying out a reaction, the device comprising:
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a first part having a first surface; at least one first area located along a portion of the first surface, the at least one first area configured to maintain at least one first substance; a second part having a second surface opposed to the first surface; and at least one second area located along a portion of the second surface, the at least one second area configured to maintain at least one second substance, wherein at least one of the first surface of the first part and the second surface of the second part is configured to move relative to the other between a first position, where the at least one first area is not exposed to the at least one second area, and a second position, where one of the at least one first areas is only exposed to one of the at least one second areas and form a closed system. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A device for carrying out a reaction, the device comprising:
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a first part having a first surface; a plurality of first areas formed along a portion of the first surface, each of the plurality of first areas configured to maintain at least one first substance; a second part having a second surface opposed to the first surface; and a plurality of second areas formed along a portion of the second surface, each of the plurality of second areas configured to maintain at least one second substance, wherein at least one of the first surface of the first part and the second surface of the second part is configured to slide relative to the other between a first position, where at least some of the plurality of first areas are not exposed to any of the plurality of second areas, and a second position in a direction substantially perpendicular to the normal of the first surface, wherein in the second position at least one of the plurality of first areas and at least one of the plurality of the second areas are only exposed to one another. - View Dependent Claims (21, 22, 23)
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24. A device for carrying out a reaction, the device comprising:
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a first part having a first surface; a first area located along a portion of the first surface, the first area configured to maintain at least one first substance; an upper second part having a second surface facing the first surface; a second area located along a portion of the second surface configured to maintain at least one second substance; and an intermediate third part disposed between the first surface of the first part and the second surface of the upper second part, the intermediate third part having an opening formed therethrough; wherein the first part, the upper second part and the intermediate third part are configured to slide relative to one another, from a first position where the first area is not exposed to the second area via the opening to a second position where the first area is exposed to the second area via the opening.
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25. A kit for carrying out a reaction, comprising:
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(a) a first part having (i) a first surface and (ii) a plurality of first areas formed along a portion of the first surface, each of the plurality of first areas configured to maintain at least one first substance; (b) a second part having (i) a second surface and (ii) a plurality of second areas formed along a portion of the second surface, each of the plurality of second areas configured to maintain at least one second substance; and (c) at least one of the at least one first substance in the at least one first area, the at least one second substance in the at least one second area, and a substrate disposed between the first surface and the second surface; wherein the first surface of the first part and the second surface of the second part are configured such that when fitted together they are opposed to each other and slide relative to the other between a first position, where at least some of the plurality of first areas are not exposed to any of the plurality of second areas, and a second position in a direction substantially perpendicular to the normal of the first surface, wherein in the second position at least one of the plurality of first areas and at least one of the plurality of the second areas are only exposed to one another.
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26. A microfluidic mixing device comprising:
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a base plate; a top plate in close contact with the base plate and moveable in a direction transverse to the plane of the plates from a first position to a second position;
the base plate comprising a plurality of wells for containing a fluid and a fluid channel, the top plate comprising a plurality of wells;
wherein when the top plate is in the first position, the channel in the base plate is in fluid contact with the wells in the top plate, and wherein when the top plate is in the second position, the wells of the base plate are in fluid contact with pre-selected wells of the top plate to form a mixing chamber.
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27. A microfluidic mixing device comprising:
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a base plate; a top plate in close contact with the base plate and moveable relative to the base plate from a first position to a second position;
the base plate comprising a plurality of wells for containing a fluid and a fluid channel, the top plate comprising a plurality of wells;
wherein when the top plate is in the first position, the channel in the base plate is in fluid contact with the wells in the top plate, and wherein when the top plate is in the second position, the wells of the said bottom plate are in fluid contact with pre-selected wells of the top plate to form a mixing chamber. - View Dependent Claims (28)
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Specification