Antiseptic Liquid Formulation, A Method for Its Use, and A Method for Preparing the Formulation

• US 20120034314A1
• Filed: 08/05/2010
• Published: 02/09/2012
• Est. Priority Date: 08/05/2010
• Status: Abandoned Application

• Current Assignee: Derma-Glove, LLC
• Original Assignee: Derma-Glove, LLC
• Inventors: Levison, Lisa Turner, Forshee, Christine Anne, Gronewald, Kerry Hays
• Application Number:
  US12/851,154
• Publication Number:
  US 20120034314A1
• Time in Patent Office: Days
• US Class Current: 424/618
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 31/02 Acyclic compounds
• CPC Class Codes: A01N 31/08 Oxygen or sulfur directly attached to an aromatic ring system
• CPC Class Codes: A01N 33/12 Quaternary ammonium compounds
• CPC Class Codes: A01N 47/44 Guanidine; Derivatives thereof
• CPC Class Codes: A01N 59/16 Heavy metals; Compounds thereof
• CPC Class Codes: A01N 59/20 Copper
• CPC Class Codes: A61K 8/042 Gels
• CPC Class Codes: A61K 8/19 containing inorganic ingredients
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/8182 Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 19/10 Washing or bathing preparations

Abstract

An antiseptic formulation capable of providing antimicrobial properties over an extended period of time is disclosed. The formulation includes chelated metal ions and a fixative polymer with the capacity to bond the chelated metal ions to the skin. This fixative polymer, polyquaternium-69 has the ability to bond chelated metal ions, and other types of antimicrobial agents, to the skin for periods of hours or days depending on the conditions in which it is used. An antiseptic liquid formulation can be integrated in a soap product and a spray product. An antiseptic gel formulation is further disclosed.

Claims

1. An antiseptic liquid formulation comprising:

polyquaternium-69;

a sufficient amount of ethyl alcohol required to dissolve said polyquaternium-69;

chelated metal ions; and

water.

2. The antiseptic liquid formulation of claim 1, wherein the chelated metal ion is silver ion.

3. The antiseptic liquid formulation of claim 1, wherein the chelated metal ion is copper ion.

4. The antiseptic liquid formulation of claim 1, further comprising a surfactant.

5. The antiseptic liquid formulation of claim 1, further comprising a gelling agent.

6. The antiseptic liquid formulation of claim 1, further comprising Irgasan DP 300 USP.

7. The antiseptic liquid formulation of claim 1, further comprising thymol.

8. The antiseptic liquid formulation of claim 1, further comprising chlorhexidine gluconate.

9. The antiseptic liquid formulation of claim 1, further comprising quaternary ammonium compounds such as benzalkonium chloride.

10. The antiseptic liquid formulation of claim 1, further comprising cetyl trimethylammonium bromide.

11. The antiseptic liquid formulation of claim 1, further comprising cetylpyridinium chloride.

12. The antiseptic liquid formulation of claim 1, further comprising benzethonium chloride.

13. A method for preparing an antiseptic liquid formulation, comprising the steps of:

adding and combining water and ethyl alcohol in a first container;

adding and combining water, silver dihydrogen citrate, acrylate crosspolymer, surfactants and gelling agents in a second container;

adding and combining the contents of the first container with the second container;

adjusting the pH to between 6 and 9;

adding and combining ethyl alcohol and polyquaternium-69 in a third container; and

adding and combining the contents of the third container and the previously combined contents of the first and second containers.

14. The method of claim 13, which further comprises the step of adding and combining Irgasan DP 300 USP to the water and ethyl alcohol in a first container.

15. The method of claim 13, which further comprises the step of adding and combining thymol to the water and ethyl alcohol in a first container.

16. The method of claim 13, which further comprises the step of adding and combining chlorhexidine gluconate to the water and ethyl alcohol in a first container.

17. The method of claim 13, which further comprises the step of adding and combining quaternary ammonium compounds such as benzalkonium chloride to the water and ethyl alcohol in the first container.

18. The method of claim 13, which further comprises the step of adding and combining cetyl trimethylammonium bromide to the water and ethyl alcohol in the first container.

19. The method of claim 13, which further comprises the step of adding and combining cetylpyridinium chloride to the water and ethyl alcohol in the first container.

20. The method of claim 13, which further comprises the step of adding and combining benzethonium chloride to the water and ethyl alcohol in the first container.

21. A method for using an antiseptic liquid formulation, comprising the steps of:

applying an antiseptic liquid formulation to the skin comprising polyquaternium-69, ethyl alcohol, water, silver dihydrogen citrate, acrylate crosspolymer, surfactants and gelling agents; and

allowing the antiseptic liquid formulation time to bond to the skin.

22. A hand-sanitizing gel formulation comprising:

58-95% ethyl alcohol by weight;

7-40% water by weight;

2-7% glycereth-18 by weight;

2-6% polyoxyethylene (20) sorbitan monooleate by weight;

0.1-2% 2-amino-2-methyl-1-propanol by weight;

0.1-2% acrylate crosspolymer by weight;

0.5-1% polyquaternium-69 by weight;

0.1-0.9% silver dihydrogen citrate by weight; and

0.3-2% Irgasan DP 300 USP by weight.

23. A hand-sanitizing spray formulation comprising:

58-95% ethyl alcohol by weight;

7-40% water by weight;

1-6% Glycereth-18 by weight;

1-6% Polyoxyethylene (20) Sorbitan Monooleate by weight;

0.5-1% Polyquaternium-69 by weight;

0.1-0.9% Silver dihydrogen citrate by weight; and

0.3-2% Irgasan DP 300 USP by weight.

24. An antibacterial soap formulation comprising:

25-36% water by weight;

25-35% sodium laureth sulfate by weight;

10-20% sodium laurel sulfate by weight;

0.1-6% hydrolyzed jojoba esters by weight;

1-5% propylene glycol by weight;

1-5% cocamidopropyl betaine by weight;

2-4% ethyl alcohol by weight;

1-5% sodium laureth sulfate by weight;

2-3% cocamide DEA by weight;

1-1.9% macadamia glycerides by weight;

0.5-10% acrylate crosspolymer by weight;

0.2-1% polyquaternium-69 by weight;

0.1-0.5% phenoxyethanol by weight;

0.1-0.9% silver dihydrogen citrate by weight;

0.3-2% Irgasan DP 300 USP by weight; and

0.1-0.5% tetrasodium EDTA by weight.