CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION
First Claim
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1. A compound of formula (I), or pharmaceutically acceptable salts or prodrugs thereof:
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Abstract
The invention features compounds of formula I or II:
In one embodiment, the invention relates compounds and processes for conjugating ligand to oligonucleotide. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, cancers, allergies, autoimmune diseases, immunodeficiencies and immunosuppression.
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Citations
27 Claims
- 1. A compound of formula (I), or pharmaceutically acceptable salts or prodrugs thereof:
- 2. A compound of formula (II), or pharmaceutically acceptable salts or prodrugs thereof:
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6-8. -8. (canceled)
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