LAPAROSCOPIC HIFU PROBE

• US 20120035473A1
• Filed: 12/29/2010
• Published: 02/09/2012
• Est. Priority Date: 03/10/2003
• Status: Abandoned Application

• Current Assignee: Focus Surgery, Inc. (Sonacare Medical, LLC)
• Original Assignee: Focus Surgery, Inc. (Sonacare Medical, LLC)
• Inventors: Sanghvi, Narendra T., Seip, Ralf, Fedewa, Russell J., Carlson, Roy F., Chen, Wo-Hsing, Katny, Artur P.
• Application Number:
  US12/981,076
• Publication Number:
  US 20120035473A1
• Time in Patent Office: Days
• US Class Current: 600/439
• CPC Class Codes: A61B 17/2251 characterised by coupling elements between the apparatus, e.g. shock wave apparatus or locating means, and the patient, e.g. details of bags, pressure control of bag on patient
• CPC Class Codes: A61B 2017/2253 using a coupling gel or liquid
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61B 8/481 involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream analysis of echo signal exploiting properties of a contrast enhancer in devices for short-range imaging with acoustic waves G01S7/52039
• CPC Class Codes: A61N 2007/0052 using the same transducer for therapy and imaging
• CPC Class Codes: A61N 2007/0065 Concave transducers
• CPC Class Codes: A61N 2007/0091 with moving parts, e.g. transducers, lenses, reflectors
• CPC Class Codes: A61N 7/00 Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092
• CPC Class Codes: A61N 7/022 intracavitary

Abstract

A high-intensity focused ultrasound ablation of tissue using minimally invasive medical procedures is provided.

Claims

1-25. -25. (canceled)

26. An apparatus for treating a targeted area of a tissue, the apparatus comprising:

a housing formed to include an aperture therein;

a transducer located within the housing, the transducer configured to emit ultrasound energy through the aperture in the housing to provide HIFU Therapy to the targeted area, the transducer configured to sense ultrasound energy;

an expandable membrane coupled to the housing, the membrane being configured to expand in a treatment direction to couple the transducer to the targeted area acoustically; and

a controller coupled to the transducer, the controller configured to cause the transducer to provide substantially continuous HIFU Therapy to a treatment path within the targeted area of tissue for a predetermined period of time, the controller switching to an imaging mode after the predetermined period of time wherein images of the tissue are obtained by ultrasound energy sensed by the transducer, the controller resuming the substantially continuous HIFU Therapy after the images are obtained.

a shim positioned over the bolus on an opposite side of the housing from the aperture, the shim being configured to block expansion of the bolus in a direction opposite from the treatment direction;

first and second coupling members located on the housing at opposite ends of the aperture and circumscribing the bolus, the first and second coupling members being configured to couple first and second portions of the bolus and first and second portions of the shim, respectively, to the housing; and

a fluid circulation system coupled to the housing to control a supply of a fluid to the housing to expand the bolus in the treatment direction prior to providing HIFU Therapy to the targeted area.

27. The apparatus of claim 26, wherein the membrane is a flexible tubular membrane inserted over the housing so that a portion of the membrane covers the aperture.

28. The apparatus of claim 27, wherein the membrane has a memory characteristic to provide a substantially flat elevated surface of the membrane located above the aperture formed in the housing.

29. The apparatus of claim 26, wherein first and second coupling members are first and second heat-shrink tubes, respectively, located on the housing at opposite ends of the aperture, the first and second heat-shrink tubes being configured to couple first and second portions of the bolus, respectively, to the housing.

30. The apparatus of claim 29, wherein the first and second heat-shrink tubes each have a thickness less than or equal to about 5/1000 of an inch.

31. The apparatus of claim 26, further comprising a drive mechanism coupled to the transducer, the drive mechanism being configured to move the transducer back and forth along a longitudinal axis of the transducer and to rotate the transducer about the longitudinal axis to provide HIFU Therapy, and a controller coupled to the drive mechanism.

32. The apparatus of claim 26, wherein the housing is configured to be inserted through a trocar for performing a laparoscopic procedure, the fluid circulation system being configured to expand the membrane after the housing, transducer, and membrane are inserted into a patient through the trocar.

33. The apparatus of claim 26, wherein a fluid circulation system provides degassed, distilled and sterile water to the housing.

34. The apparatus of claim 26, wherein the controller is configured to cause the transducer to provide substantially continuous HIFU Therapy such that a transducer focal zone tissue region is ablated.

35. The apparatus of claim 26, wherein the apparatus is configured to provide HIFU Therapy to a HIFU focal zone to modify at least one property of the tissue in the HIFU focal zone such that tissue located between the transducer and the focal zone is ablated.

36. The apparatus of claim 35, wherein the property of the tissue includes at least one of absorption, impedance and attenuation.

37. The apparatus of claim 26, wherein the predetermined period of time is substantially longer than the time required to obtain the images in the imaging mode.

38. The apparatus of claim 26, wherein the predetermined period of time is about 30 seconds.

39. The apparatus of claim 26, wherein the imaging mode has a duration of about 1 second.

40. The apparatus of claim 26, wherein the controller changes direction of the treatment path by an angle of about 90 degrees when the treatment path reaches a boundary of the treatment region defined by the physician.

41. The apparatus of claim 34, wherein at least one tissue property of the focal zone tissue region changes such that HIFU energy is not delivered to any tissue region located at a distance further from the focal zone tissue region away from the transducer.

42. The apparatus of claim 41, wherein the tissue property includes at least one of absorption, impedance, and attenuation.

43. A method for treating a targeted area of tissue, the method comprising the steps of:

administering a substantially continuous HIFU Therapy to a treatment path within the targeted area of tissue for a predetermined period of time;

stopping the HIFU Therapy treatment after the predetermined period of time;

generating a visual representation of the tissue; and

resuming the HIFU Therapy treatment after the visual representation is obtained.

44. The method of claim 43, wherein the step of administering the HIFU Therapy results in a focal zone tissue region being ablated.

45. The method of claim 43 further comprising the step of providing HIFU Therapy to a HIFU focal zone to modify at least one property of the tissue in the HIFU focal zone such that tissue located between the transducer and the focal zone is ablated.

46. The method of claim 45, wherein the property of the tissue includes at least one of absorption, impedance and attenuation.

47. The method of claim 43, wherein the predetermined period of time is substantially longer than the time required to obtain the images in the imaging mode.

48. The method of claim 43, wherein the predetermined period of time is about 30 seconds.

49. The method of claim 43, wherein the imaging mode has a duration of about 1 second.

50. The method of claim 44, wherein at least one tissue property of the focal zone tissue region changes such that HIFU energy is not delivered to any tissue region located at a distance further from the focal zone tissue region away from the transducer.

51. The method of claim 50, wherein the tissue property includes at least one of absorption, impedance, and attenuation.

52. The method of claim 43, wherein the HIFU Therapy is administered by a transducer located within a housing.

53. The method of claim 52, wherein an expandable membrane is coupled to the housing, the expandable membrane configured to expand in a treatment direction to couple the transducer to the targeted area acoustically.

54. The method of claim 53, wherein the expandable membrane has a memory characteristic to provide a substantially flat elevated surface of the membrane above the aperture formed in the housing.

55. The method of claim 43, wherein a drive mechanism is coupled to the transducer, the drive mechanism being configured to move the transducer back and forth along a longitudinal axis of the transducer and to rotate the transducer about the longitudinal axis to provide HIFU Therapy.

56. The method of claim 55, where in a controller is coupled to the drive mechanism.

57. The method of claim 52, wherein the housing is configured to be inserted through a trocar for performing a laparoscopic procedure.

58. The method of claim 53, wherein a fluid circulation system is coupled to the housing to control a supply of a fluid to the housing to expand the membrane in a treatment direction prior to providing HIFU Therapy.

59. The method of claim 56, wherein the controller changes direction of a treatment path by an angle of about 90 degrees when the treatment path reaches a boundary of a treatment region.