DRUG TITRATION UTILIZING AN IMPLANTABLE MEDICAL DEVICE

• US 20120035486A1
• Filed: 10/18/2011
• Published: 02/09/2012
• Est. Priority Date: 08/07/2007
• Status: Abandoned Application

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Zhang, Yunlong, Zhang, Yi
• Application Number:
  US13/275,741
• Publication Number:
  US 20120035486A1
• Time in Patent Office: Days
• US Class Current: 600/484
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/076 Permanent implantations telemetry using implanted circuitry A61B5/0031; implanted stimulators for therapy A61N1/3605, A61N1/362, A61N1/372
• CPC Class Codes: A61B 5/0809 by impedance pneumography
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 2205/3523 using telemetric means
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/37282 characterised by communication with experts in remote locations using a network

Abstract

A method of monitoring patient status is disclosed. Electrical signals are received from one or more implanted sensors of a cardiac rhythm management device. Two or more index values are calculated from the electrical signals. A composite index is determined from the two or more index values, and a status notification associated with the composite index is provided. In a system for monitoring patient status, a processor is configured to receive electrical signals from an implanted cardiac rhythm management device, calculate two or more index values from the electrical signals, and determine a composite index from the two or more index values. The system incorporates a memory that is in communication with the processor and an interface in communication with the processor, where the interface is configured to communicate a status notification associated with the composite index.

Claims

1. A method of monitoring patient status comprising:

(i) receiving electrical signals from one or more implanted sensors of a cardiac rhythm management device;

(ii) calculating two or more index values from the electrical signals;

(v) determining a composite index from the two or more index values; and

(vi) providing a status notification associated with the composite index.

2. The method of claim 1, wherein each of the two or more index values represents the severity of a physical characteristic.

3. The method of claim 1, wherein the composite index defines a recommended degree of oversight of a patient.

4. The method of claim 1, further comprising processing the electrical signals to measure physical characteristics.

5. The method of claim 4, wherein measuring physical characteristics comprises determining the presence and degree of arrhythmias.

6. The method of claim 4, wherein measuring physical characteristics comprises determining mean arterial pressure.

7. The method of claim 4, wherein measuring physical characteristics comprises determining pulmonary edema status.

8. The method of claim 4, wherein measuring physical characteristics comprises determining the presence and degree of dyspnea.

9. The method of claim 4, wherein measuring physical characteristics comprises determining CSR/AHI burden.

10. The method of claim 1, wherein determining the composite index occurs only when the sensor indicates that the patient is in a pre-selected state.

11. The method of claim 10, wherein the pre-selected state corresponds to the patient being at rest and supine.

12. The method of claim 1, further comprising determining if a scheduled titration event interval has been exceeded, and generating a signal that is indicative of the fact that the schedule titration event interval has been exceeded.

13. A medical device system for monitoring patient status, comprising:

(i) a processor configured to

receive electrical signals from an implanted cardiac rhythm management device,

calculate two or more index values from the electrical signals, and

determine a composite index from the two or more index values;

(ii) a memory in communication with the processor; and

(iii) an interface in communication with the processor, wherein the interface is configured to communicate a status notification associated with the composite index.

14. The medical device system of claim 13, wherein the processor is further configured for communication with one or more implanted sensors.

15. The medical device system of claim 13, wherein the processor is further configured to measure physical characteristics from the received electrical signals.

16. The medical device system of claim 13, wherein each of the two or more index values represents the severity of a physical characteristic.

17. The medical device system of claim 13, wherein the status notification comprises an indication of drug tolerance.

18. The medical device system of claim 15, wherein measuring physical characteristics comprises determining the presence and degree of arrhythmia.

19. The medical device system of claim 15, wherein measuring physical characteristics comprises determining mean arterial pressure.

20. The medical device system of claim 15, wherein measuring physical characteristics comprises determining pulmonary edema status.