METHOD AND APPARATUS FOR IN VIVO COLLECTION OF CIRCULATING BIOLOGICAL COMPONENTS
First Claim
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1. A biological surveillance probe for detecting disease, comprisingan elongate body having a proximal end and a distal end;
- an attraction structure attached to the elongate body, wherein the attraction structure is capable of attracting a binding agent.
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Abstract
The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis. In some embodiments of the invention, active attraction of biological markers are provided. A partial or complete analytic/detection assembly may also be integrated with the probe.
5 Citations
29 Claims
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1. A biological surveillance probe for detecting disease, comprising
an elongate body having a proximal end and a distal end; an attraction structure attached to the elongate body, wherein the attraction structure is capable of attracting a binding agent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method for detecting disease, comprising the steps of:
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providing a binding agent attraction device; inserting the device into a body; introducing a binding agent into the body; attracting at least a portion of the binding agent to the attraction device; and assessing the binding agent attracted to the attraction device. - View Dependent Claims (19, 20)
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Specification