Mitral Prosthesis and Methods for Implantation
First Claim
1. A mitral valve prosthesis for implantation in an annulus of a native mitral valve, including a frame, the frame comprising:
- a first expandable inflow region formed of a plurality of cells and configured to expand within and support against the walls of the left atrium, wherein the first expandable inflow region has a cross-sectional diameter larger than the annulus of the native mitral valve; and
a second expandable outflow region formed of a plurality of cells and configured to expand within and support against the native mitral valve annulus.
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Accused Products
Abstract
A mitral valve prosthesis and methods for implanting the prosthesis transapically (i.e., through the apex of the heart), transatrially (i.e., through the left atrium of the heart), and transseptally (i.e., through the septum of the heart). The prosthesis generally includes a self-expanding frame and two or more support arms. A valve prosthesis is sutured to the self-expanding frame. Each support arm corresponds to a native mitral valve leaflet. At least one support arm immobilizes the native leaflets, and holds the native leaflets close to the main frame.
341 Citations
16 Claims
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1. A mitral valve prosthesis for implantation in an annulus of a native mitral valve, including a frame, the frame comprising:
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a first expandable inflow region formed of a plurality of cells and configured to expand within and support against the walls of the left atrium, wherein the first expandable inflow region has a cross-sectional diameter larger than the annulus of the native mitral valve; and a second expandable outflow region formed of a plurality of cells and configured to expand within and support against the native mitral valve annulus. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 14)
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12. A method of treating a mitral valve disorder in a patient'"'"'s heart, comprising:
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making an incision in the heart; inserting a trocar through the incision in the heart; advancing a mitral valve prosthesis through the trocar and into the heart, wherein the mitral valve prosthesis includes; an expandable inner support structure formed of a plurality of cells and having a distal section, a throat section, and a proximal section, wherein the proximal section has a cross-sectional area greater than the throat section and the distal section, respectively; an expandable outer support structure having two or more engagement arms and two or more commissure posts, wherein ends of the engagement arms are each coupled to one of the commissure posts, wherein the engagement arms are upwardly concave such as to form a trough adjacent to the throat section of the inner support structure, and wherein the distal section of the inner support structure is coupled to the commissure posts of the outer support structure; a valve prosthesis sutured to the inner support structure; releasing the engagement arms from the trocar; advancing the trocar into the native mitral valve such that the engagement arms sit on the outer surface of the native mitral valve leaflets; releasing the inner support structure from the trocar; and withdrawing the trocar from the heart.
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15. A method of treating a mitral valve disorder in a patient'"'"'s heart, comprising:
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making an incision in an apical area of the heart; inserting a trocar through the incision in the apical area of the heart and into the left ventricle of the heart; advancing a mitral valve prosthesis through the trocar and into the left ventricle of the heart, wherein the mitral valve prosthesis includes; an expandable inner support structure formed of a plurality of cells and having a distal section, a throat section, and a proximal section, wherein the proximal section has a cross-sectional area greater than the throat section and the distal section, respectively; an expandable outer support structure having two or more engagement arms and two or more commissure posts, wherein an end of each engagement arm is coupled to one of the commissure posts, wherein the engagement arms are upwardly concave such as to form a trough adjacent to the throat section of the inner support structure, and wherein the distal section of the inner support structure is coupled to the commissure posts of the outer support structure; and a valve prosthesis sutured to the inner support structure; releasing the engagement arms from the trocar; advancing the trocar to the native mitral valve annulus such that the engagement arms sit on the outer surface of the native mitral valve leaflets; releasing the inner support structure from the trocar; withdrawing the trocar from the heart; and closing the incision in the apex of the heart.
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16. A method of treating a mitral valve disorder in a patient'"'"'s heart, comprising:
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making an incision in a femoral vein; inserting a trocar through the incision in the femoral vein and advancing the trocar into the right atrium of the heart; making an incision in the septum of the heart; advancing the trocar through the incision in the septum of the heart and into the left atrium; advancing a mitral valve prosthesis through the trocar and into the left atrium of the heart, wherein the mitral valve prosthesis includes; an expandable inner support structure formed of a plurality of cells and having a distal section, a throat section, and a proximal section, wherein the proximal section has a cross-sectional area greater than the throat section and the distal section, respectively; an expandable outer support structure having two engagement arms and two commissure posts, wherein an end of each engagement aim is coupled to one of the commissure posts, wherein the engagement arms are upwardly concave such as to form a trough adjacent to the throat section of the inner support structure, and wherein the distal section of the inner support structure is coupled to the commissure posts of the outer support structure; and a valve prosthesis sutured to the inner support structure; advancing the trocar past the native mitral valve and into the left ventricle of the heart; releasing the engagement arms from the trocar; retracting the trocar such that the engagement arms sit on the outer surface of the native mitral valve leaflets; releasing the inner support structure from the trocar; closing the incision in the septum; and withdrawing the trocar from the heart.
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Specification