NON-INVASIVE BIOMEDICAL DETECTION AND MONITORING SYSTEMS
First Claim
Patent Images
1. A method for non-invasively and continuously extracting interstitial fluid from a subject comprising the steps of:
- irreversibly electroporating the skin;
applying a negative pressure at or near the region of the skin irreversibly electroporated for extracting the interstitial fluid; and
collecting the extracted interstitial fluid from the skin.
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Abstract
The present disclosure relates to a non-invasive and continuous biomedical detections and non-invasive and continuous monitoring methods and devices for extracting and analyzing interstitial fluid extracted non-invasively and continuously from the skin of a subject comprising non-invasively electroporating the skin using a non pulsed voltage in combination with a pulsed voltage and applying negative pressure
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Citations
45 Claims
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1. A method for non-invasively and continuously extracting interstitial fluid from a subject comprising the steps of:
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irreversibly electroporating the skin; applying a negative pressure at or near the region of the skin irreversibly electroporated for extracting the interstitial fluid; and collecting the extracted interstitial fluid from the skin. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A device for non-invasively and continuously extracting interstitial fluid from the skin of a subject comprising:
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means for irreversibly electroporating the skin by generating a non pulsed voltage and a pulsed voltage between at least one first moving or stationary electrode and a second stationary electrode; a vacuum pump providing a negative pressure above the skin; and a collecting chamber for collecting the interstitial fluid extracted from the skin. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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35. A method for electro-suturing the skin from a subject comprising the steps of:
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irreversibly electroporating the skin; applying a negative pressure at or near the region of the skin irreversibly electroporated for suturing the skin and for extracting the interstitial fluid; and collecting the extracted interstitial fluid from the skin. - View Dependent Claims (36, 37, 38, 39, 40, 41, 42, 43, 44, 45)
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Specification