AORTIC VALVE STENT GRAFT

• US 20120046726A1
• Filed: 11/02/2011
• Published: 02/23/2012
• Est. Priority Date: 11/09/2007
• Status: Active Grant

• Current Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Original Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Inventors: Chuter, Timothy AM
• Granted Patent: US 10,105,218 B2
• Time in Patent Office: Days
• US Class Current: 623/1.2
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0007 for adjusting length
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2250/006 modular

Abstract

An implantable endoluminal prosthesis for replacing a damaged aortic valve is provided. In one embodiment, the prosthesis includes a balloon-expandable stent, a tubular conduit that extends into the ascending aorta, and a self-expanding stent. The tubular conduit extends across the balloon-expandable stent. The tubular conduit includes an artificial valve. The self-expanding stent extends across the tubular conduit into the ascending aorta. The balloon-expandable stent, the tubular conduit, and the self-expanding stent are coupled to provide unidirectional flow of fluid into the aorta and further into the coronary arteries. Also provided is a method for implanting the endoluminal prosthesis.

Claims

1-20. -20. (canceled)

21. An endoluminal prosthesis comprising:

at least one stent; and

a tubular conduit comprising an aortic valve replacement, wherein at least a portion of the tubular conduit overlaps at least a portion of the at least one stent,

wherein a distal end of the tubular conduit terminates at a location between proximal and distal ends of the at least one stent, and

wherein the at least one stent comprises at least one uncovered region to allow fluid to pass radially outside of an outer perimeter of the at least one stent after passing through the aortic valve replacement.

22. The endoluminal prosthesis of claim 21, wherein the at least one stent at least partially surrounds the tubular conduit.

23. The endoluminal prosthesis of claim 21, wherein the at least one stent comprises a balloon-expandable stent.

24. The endoluminal prosthesis of claim 21, wherein the at least one stent comprises a self-expanding stent.

25. The endoluminal prosthesis of claim 21, wherein the aortic valve replacement comprises an artificial valve.

26. The endoluminal prosthesis of claim 21, wherein the aortic valve replacement is located at the distal end of the tubular conduit.

27. The endoluminal prosthesis of claim 21 further comprising one or more barbs.

28. An endoluminal prosthesis comprising:

at least one stent; and

a tubular conduit comprising an aortic valve replacement, wherein at least a portion of the tubular conduit overlaps at least a portion of the at least one stent,

wherein a distal end of the tubular conduit terminates at a location between proximal and distal ends of the at least one stent, and

wherein the at least one stent comprises a proximal zone having a first diameter and a distal zone having a second diameter, where the first diameter is narrower than the second diameter.

29. The endoluminal prosthesis of claim 28, wherein the at least one stent at least partially surrounds the tubular conduit.

30. The endoluminal prosthesis of claim 28, wherein the at least one stent comprises a balloon-expandable stent.

31. The endoluminal prosthesis of claim 28, wherein the at least one stent comprises a self-expanding stent.

32. The endoluminal prosthesis of claim 28, wherein the aortic valve replacement comprises an artificial valve.

33. The endoluminal prosthesis of claim 28, wherein the aortic valve replacement is located at the distal end of the tubular conduit.

34. The endoluminal prosthesis of claim 28 further comprising one or more barbs.

35. A method of replacing an aortic valve in a subject, the method comprising:

introducing into a vascular system an endoluminal prosthesis comprising at least one stent and a tubular conduit comprising an aortic valve replacement, wherein at least a portion of the tubular conduit overlaps at least a portion of the at least one stent;

advancing the endoluminal prosthesis within the vascular system towards an aortic annulus;

expanding at least a portion of the prosthesis into engagement with the aortic annulus; and

allowing fluid to pass radially outside of an outer perimeter of the at least one stent after passing through the aortic valve replacement.

36. The method of claim 35, wherein the at least one stent at least partially surrounds the tubular conduit.

37. The method of claim 35, wherein the at least one stent comprises a balloon-expandable stent.

38. The method of claim 35, wherein the at least one stent comprises a self-expanding stent.

39. The method of claim 35, wherein the at least one stent and the tubular conduit are provided for unidirectionally passing fluid through the prosthesis and at least inhibiting retrograde flow through the prosthesis.

40. The method of claim 35 further comprising expanding the at least one stent into engagement with at least one of the aortic annulus and the ascending aorta.