THERAPEUTIC MODULATION OF VAGINAL EPITHELIUM BOUNDARY LUBRICATION
6 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates to the management of vaginal health. In particular, the present invention relates to pharmaceutical compositions, and methods of use thereof, for treating diseases associated with compromised boundary lubrication at the vaginal epithelium.
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Citations
49 Claims
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1-27. -27. (canceled)
- 28. A method of treating decreased vaginal boundary lubrication or a disease associated therewith or of improving vaginal boundary lubrication, the method comprising topically administering to a vaginal surface of a subject in need thereof a therapeutically effective amount of isolated or purified PRG4.
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29. (canceled)
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31-32. -32. (canceled)
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33. A method of providing lubrication during intercourse or promoting conception comprising topically administering to a vaginal surface, a penile surface, or a combination thereof an effective amount of an isolated or purified PRG4.
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34-35. -35. (canceled)
- 36. A method for improving vaginal boundary lubrication comprising administering a therapeutically effective amount of isolated or purified PRG4 and a pharmaceutically acceptable carrier, wherein the therapeutically effective amount of isolated or purified PRG4 is sufficient to improve vaginal boundary lubrication.
Specification