Resveratrol-Containing Compositions And Methods Of Use
First Claim
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1. A method of modulating a biological activity in a human subject, comprising:
- administering to a human subject in need thereof a composition comprisingtrans-resveratrol in an amount of 0.25 to 5 mg per kilogram of the human subject,a metal chelating agent, andone or more additional antioxidants,wherein said administration is effective to modulate a biological activity in the human subject as compared to administration of resveratrol alone.
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Abstract
A resveratrol-containing composition capable of providing a therapeutic benefit to a subject such as modulation of a biological activity, improving cell transplantation therapy, or improving macular degeneration or dystrophy treatments. The compositions comprise trans-resveratrol, a metal chelator, and one or more additional antioxidants such as phenolic antioxidants or vitamin D.
36 Citations
20 Claims
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1. A method of modulating a biological activity in a human subject, comprising:
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administering to a human subject in need thereof a composition comprising trans-resveratrol in an amount of 0.25 to 5 mg per kilogram of the human subject, a metal chelating agent, and one or more additional antioxidants, wherein said administration is effective to modulate a biological activity in the human subject as compared to administration of resveratrol alone. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of improving cell transplantation therapy in a human subject, comprising:
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co-administering to a human subject transplanted cells and a composition comprising trans-resveratrol in an amount of 0.25 to 5 mg per kilogram of the human subject, a metal chelating agent, and one or more additional antioxidants, wherein said co-administration is effective to improve the effectiveness of the cell transplantation in the human subject as compared to administration of the transplanted cells alone. - View Dependent Claims (14, 15, 16, 17)
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18. A method of improving treatment of macular degeneration in a human subject, comprising:
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administering to a human subject suffering from macular degeneration or macular dystrophy a composition comprising trans-resveratrol in an amount of 0.25 to 5 mg per kilogram of the human subject, a metal chelating agent, and one or more additional antioxidants, wherein said administration is effective to improve the effectiveness of the macular degeneration treatment in the human subject as compared to administration of resveratrol alone. - View Dependent Claims (19, 20)
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Specification