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Tamper Resistant Dosage Form Comprising An Anionic Polymer

  • US 20120059065A1
  • Filed: 09/01/2011
  • Published: 03/08/2012
  • Est. Priority Date: 09/02/2010
  • Status: Abandoned Application
First Claim
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1. A pharmaceutical dosage form exhibiting a breaking strength of at least 500 N, said dosage form comprising:

  • a pharmacologically active ingredient (A);

    an anionic polysaccharide (B) obtainable by introducing anionic functional groups, in protonated form or a physiologically acceptable salt thereof, into a polysaccharide; and

    a polyalkylene oxide (C);

    wherein the pharmacologically active ingredient (A) is present in a controlled-release matrix comprising the anionic polysaccharide (B) and the polyalkylene oxide (C).

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