METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW
First Claim
1. A system for determining cardiovascular information for a patient, the system comprising:
- at least one computer system configured to;
receive patient-specific data regarding a geometry of at least a portion of an anatomical structure of the patient, the portion of the anatomical structure including at least a portion of the patient'"'"'s aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta;
create a three-dimensional model representing the portion of the anatomical structure based on the patient-specific data;
create a physics-based model relating to a blood flow characteristic within the portion of the anatomical structure; and
determine a fractional flow reserve within the portion of the anatomical structure based on the three-dimensional model and the physics-based model.
2 Assignments
0 Petitions
Accused Products
Abstract
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of at least a portion of an anatomical structure of the patient. The portion of the anatomical structure may include at least a portion of the patient'"'"'s aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta. The at least one computer system may also be configured to create a three-dimensional model representing the portion of the anatomical structure based on the patient-specific data, create a physics-based model relating to a blood flow characteristic within the portion of the anatomical structure, and determine a fractional flow reserve within the portion of the anatomical structure based on the three-dimensional model and the physics-based model.
167 Citations
30 Claims
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1. A system for determining cardiovascular information for a patient, the system comprising:
at least one computer system configured to; receive patient-specific data regarding a geometry of at least a portion of an anatomical structure of the patient, the portion of the anatomical structure including at least a portion of the patient'"'"'s aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta; create a three-dimensional model representing the portion of the anatomical structure based on the patient-specific data; create a physics-based model relating to a blood flow characteristic within the portion of the anatomical structure; and determine a fractional flow reserve within the portion of the anatomical structure based on the three-dimensional model and the physics-based model. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for determining patient-specific cardiovascular information using at least one computer system, the method comprising:
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inputting into the at least one computer system patient-specific data regarding a geometry of at least a portion of an anatomical structure of the patient, the portion of the anatomical structure including at least a portion of the patient'"'"'s aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta; creating, using the at least one computer system, a three-dimensional model representing the portion of the anatomical structure based on the patient-specific data; creating, using the at least one computer system, a physics-based model relating to a blood flow characteristic within the portion of the anatomical structure; and determining, using the at least one computer system, a fractional flow reserve within the portion of the anatomical structure based on the three-dimensional model and the physics-based model. - View Dependent Claims (12, 13, 14, 15, 16)
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17. A system for determining cardiovascular information for a patient, the system comprising:
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at least one computer system configured to; receive patient-specific imaging data regarding a geometry of at least a portion of an anatomical structure of the patient, the portion of the anatomical structure including at least a portion of the patient'"'"'s aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta; create a three-dimensional model representing the portion of the anatomical structure based on the patient-specific imaging data, the three-dimensional model including portions representing a plurality of outlets for blood flow formed by the plurality of coronary arteries; and determine fractional flow reserve at a plurality of locations within the portion of the anatomical structure based on the three-dimensional model and at least one physics-based model; wherein the at least one physics-based model represents a blood flow through at least one of the plurality of outlets, the at least one physics-based model having less than three dimensions; and wherein the fractional flow reserve indicates a ratio between a pressure at a first location in the plurality of coronary arteries and a second location upstream from the first location. - View Dependent Claims (18, 19, 20, 21, 22, 23)
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24. A method for determining patient-specific cardiovascular information using at least one computer system, the method comprising:
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inputting into the at least one computer system patient-specific imaging data regarding a geometry of at least a portion of an anatomical structure of the patient, the portion of the anatomical structure including at least a portion of the patient'"'"'s aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta; creating, using the at least one computer system, a three-dimensional model representing the portion of the anatomical structure based on the patient-specific imaging data, the three-dimensional model including portions representing a plurality of outlets for blood flow formed by the plurality of coronary arteries; and determining, using the at least one computer system, fractional flow reserve at a plurality of locations within the portion of the anatomical structure based on the three-dimensional model and at least one physics-based model; wherein the at least one physics-based model represents a blood flow through at least one of the plurality of outlets, the at least one physics-based model having less than three dimensions; and wherein the fractional flow reserve indicates a ratio between a pressure at a first location in the plurality of coronary arteries and a second location upstream from the first location. - View Dependent Claims (25, 26, 27, 28, 29, 30)
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Specification