CELL-BASED SENSING SYSTEMS AND METHODS
First Claim
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1. A sensing system comprising:
- one or more cells that change configuration and/or move as a result of presence of substances, change in environment, or intrinsic physiological change; and
an individual sensing unit or an array of sensing units, each sensing unit comprising at least one sensor, the at least one sensor being coupled with the one or more cells such that the change of configuration and/or movement of the one or more cells changes one or more electrical and/or mechanical parameters of the at least one sensor as a function of the change of configuration and/or movement of the one or more cells.
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Abstract
The present disclosure describes cell-based sensors. Cell-based sensors can comprise cells coupled with a sensor for sensing change of configuration and/or movement of the cells. Such changes of configuration and/or movement of the cells can be sensed through changes to one or more parameters such as electrical, mechanical and/or optical parameters. By way of example, the sensors can be magnetic based sensors or electrochemical sensors.
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45 Claims
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1. A sensing system comprising:
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one or more cells that change configuration and/or move as a result of presence of substances, change in environment, or intrinsic physiological change; and an individual sensing unit or an array of sensing units, each sensing unit comprising at least one sensor, the at least one sensor being coupled with the one or more cells such that the change of configuration and/or movement of the one or more cells changes one or more electrical and/or mechanical parameters of the at least one sensor as a function of the change of configuration and/or movement of the one or more cells. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A sensing method comprising:
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providing one or more cells that change configuration and/or move as a result of presence of substances in an analyte, environmental change or intrinsic physiological change, wherein the substances are at or near the one or more cells; coupling one or more sensors with the one or more cells, the one or more cells changing one or more electrical and/or mechanical parameters of the one or more sensors as a function of the change of configuration and/or movement of the one or more cells; applying one or more analytes; and detecting the change of the one or more electrical and/or mechanical parameters of the one or more sensors as a function of the change of configuration and/or movement of the one or more cells, whereby the detected change of the one or more electrical and/or mechanical parameters corresponds to the presence or absence of the substances, environmental changes and/or physiological changes in the one or more analytes. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45)
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Specification