Redox Polymer Based Reference Electrodes Having An Extended Lifetime For Use In Long Term Amperometric Sensors
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Abstract
The present application provides redox polymer based reference electrodes having an extended lifetime that are suitable for use in long term amperometric sensors. Electrochemical sensors equipped with reference electrodes described herein demonstrate considerable stability and extended lifetime in a variety of conditions.
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Citations
63 Claims
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1-45. -45. (canceled)
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46. A method for monitoring concentration of an analyte, the method comprising:
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inserting at least a portion of an analyte sensor into a patient, the analyte sensor comprising a working electrode and a reference electrode; applying a potential of from 150 mV to 190 mV between the working electrode and reference electrode; collecting data from the analyte sensor; and determining the analyte concentration from the collected data. - View Dependent Claims (47, 48, 49, 50, 51, 52, 53, 54, 55, 57, 58, 59, 60, 61, 62, 63)
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56. A method for monitoring concentration of an analyte, the method comprising:
inserting at least a portion of an analyte sensor into a patient, the analyte sensor comprising; a working electrode comprising a sensing layer comprising an analyte-responsive enzyme and a flux-limiting membrane disposed over the sensing layer; and a reference electrode comprising a crosslinker and a polymer having the formula;
Specification