System and method for real-time perfusion imaging
First Claim
Patent Images
1. An apparatus for imaging and measuring time-based fluctuations in a laser speckle pattern, comprising:
- a plurality of coaligned imaging arrays, each with independently controllable timing;
a coherent light source arranged for illuminating at least a portion of an imaging subject;
a lens for collecting light from the imaging subject;
a prism for presenting identical spectral content from the lens to each of the plurality of imaging arrays;
a central processing unit in electronic communication with the coherent light source and each of the plurality of imaging arrays;
a control set in electronic communication with the central processing unit, the control set for controlling the coherent light source and the plurality of imaging arrays; and
a display in electronic communication with the central processing unit.
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Abstract
The present invention relates to a system and method for real-time perfusion imaging. More particularly, the present invention relates to a perfusion imaging system including a plurality of coaligned imaging arrays operating under a specific timing sequence and method of using the same.
4 Citations
28 Claims
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1. An apparatus for imaging and measuring time-based fluctuations in a laser speckle pattern, comprising:
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a plurality of coaligned imaging arrays, each with independently controllable timing; a coherent light source arranged for illuminating at least a portion of an imaging subject; a lens for collecting light from the imaging subject; a prism for presenting identical spectral content from the lens to each of the plurality of imaging arrays; a central processing unit in electronic communication with the coherent light source and each of the plurality of imaging arrays; a control set in electronic communication with the central processing unit, the control set for controlling the coherent light source and the plurality of imaging arrays; and a display in electronic communication with the central processing unit. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method for producing a perfusion image comprising the steps of:
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a. illuminating at least a portion of an imaging subject using a coherent light source; b. collecting spectral content from said imaging subject; c. directing the spectral content to each of a plurality of imaging arrays; d. sequentially acquiring an image with each of said plurality of imaging arrays; e. processing said sequentially acquired images to generate a single perfusion image; and f. displaying the perfusion image on a display. - View Dependent Claims (23, 24, 25, 26, 27, 28)
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Specification