Implantable biochip for managing trauma--induced hemorrhage
First Claim
1. An analyte measuring device for monitoring physiological status by measuring at least one analyte, comprising:
- an insulating substrate;
a conductive material supported on the insulating substrate;
an insulating layer overlying the conductive material, the insulating layer formed in a pattern thereby passivating covered surface portions of the underlying conductive material and exposing predetermined surface portions of the conductive material, the exposed portions of the conductive material functioning as electrodes;
a polymeric biorecognition layer immediately adjacent to the insulating layer and the exposed surface portions of the conductive material, the polymeric biorecognition layer containing at least one molecular entity of biological or biomimetic origin that is specific to the at least one analyte being measured.
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Accused Products
Abstract
A biocompatible biosensor and transmitter device for temporary implantation prior to, during and following trauma-induced hemorrhaging detects the presence and level of at least one analyte and transmits detected data to a second, external device. Thus, a method for managing post-trauma patient outcomes includes providing such a biosensor and transmitter device, temporarily implanting the biocompatible biosensor and transmitter device intramuscularly in a trauma victim; and monitoring the presence and level of the at least one analyte detected by the biocompatible biosensor and transmitter device and transmitted to the external data receiving means.
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Citations
16 Claims
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1. An analyte measuring device for monitoring physiological status by measuring at least one analyte, comprising:
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an insulating substrate; a conductive material supported on the insulating substrate; an insulating layer overlying the conductive material, the insulating layer formed in a pattern thereby passivating covered surface portions of the underlying conductive material and exposing predetermined surface portions of the conductive material, the exposed portions of the conductive material functioning as electrodes; a polymeric biorecognition layer immediately adjacent to the insulating layer and the exposed surface portions of the conductive material, the polymeric biorecognition layer containing at least one molecular entity of biological or biomimetic origin that is specific to the at least one analyte being measured. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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- 10. A biocompatible biosensor and transmitter device for temporary implantation prior to, during and following trauma-induced hemorrhaging, the device detecting the presence and level of at least one analyte and transmitting detected data to a second, external data receiving device.
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15. A method for managing post-trauma patient outcomes comprising:
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providing a biocompatible biosensor and transmitter device and a data receiving means, the biocompatible biosensor and transmitter device capable of detecting the presence and level of at least one analyte and transmitting detected data to the data receiving means; temporarily implanting the biocompatible biosensor and transmitter device into a muscle of a hemorrhaging trauma victim; and employing the biosensor of the biocompatible device to collect data regarding the presence or the amount of the at least one analyte and employing the transmitter of the biocompatible device to transmit data to the data receiving means. - View Dependent Claims (16)
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Specification