Topical base and active agent-containing compositions, and methods for improving and treating skin

• US 20120100183A1
• Filed: 10/23/2010
• Published: 04/26/2012
• Est. Priority Date: 10/23/2010
• Status: Abandoned Application

• Current Assignee: Daniel Isaac Schlessinger, Joel Schlessinger
• Original Assignee: Daniel Isaac Schlessinger, Joel Schlessinger
• Inventors: Schlessinger, Joel, Schlessinger, Daniel Isaac
• Application Number:
  US12/925,464
• Publication Number:
  US 20120100183A1
• Time in Patent Office: Days
• US Class Current: 424/400
• CPC Class Codes: A61K 31/573 substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
• CPC Class Codes: A61K 47/10 Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
• CPC Class Codes: A61K 47/44 Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin synthetic glycerides, e.g. medium-chain triglycerides, A61K47/14
• CPC Class Codes: A61K 9/0014 Skin, i.e. galenical aspects of topical compositions non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00
• CPC Class Codes: A61K 9/06 Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels composition of ointments, creams or gels A61K47/00
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

The present invention provides unique, efficacious, inexpensive, safe, reliable, convenient, minimally bitter, skin protecting and penetrating, easy-to-administer base compositions and active agent-containing compositions, such as those including hydrocortisone, and related production and topical application methods, for treating the skin of mammals for a wide variety of different dermatologic conditions, disorders and diseases, such as inflammation, redness, cracking, insect bites, dryness, allergic reactions, trauma, irritant dermatitis, perleche, contact dermatitis, psoriasis, eczema, seborrheic dermatitis, acne excoriate, xerosis, eczema craquele, stasis dermatitis, disease related conditions and dryness from medications such as isotretinoin, acitretin and lipid lowering agents. This is effected by topically administering, or otherwise applying, effective amounts of the compositions thereto in forms that not only address the skin and mucosa of the mouth and lips, but also of the rest of the body and, in particular, areas where other topical balms containing hydrocortisone and other active ingredients have not been developed or marketed. Additionally, the flavoring addition to this product, and the base wherein the active ingredient(s) reside, affords a significantly better tasting, and less bitter, composition, thereby allowing a more pleasant experience and better compliance by patients. Larger sized stick formulation(s) allow for more applicability of the product, and more usefulness thereof, in various areas, and mucosal skin, of the body. The compositions include a unique formulation of FANCOL VB, Natunola Castor 1023, Finsolv TN, bees wax and, optionally, one or a plurality of plant or plant seed oils, fatty alcohols, fats and flavorings, in desirable weight percents thereof, in various forms, and preferably in the form of a solid roll-on stick present in a variety of sizes.

Claims

1. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, comprising FANCOL VB, Natunola Castor 1023, Finsolv TN and bees wax, each in amounts that are effective for collectively forming a base composition in a sold form having an ability to function effectively as a topically-applied carrier vehicle for the active agents.

2. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, consisting essentially of FANCOL VB, Natunola Castor 1023, Finsolv TN and bees wax, each in amounts that are effective for collectively forming a base composition in a sold form having an ability to function effectively as a topically-applied carrier vehicle for the active agents.

3. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, comprising FANCOL VB, Natunola Castor 1023, Finsolv TN and bees wax, and one or a plurality of plant oils, plant seed oils, fatty alcohols or fats, or any combination thereof, each in combined amounts that are effective for collectively forming a base composition in a sold form having an ability to function effectively as a topically-applied carrier vehicle for the active agents.

4. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, consisting essentially of FANCOL VB, Natunola Castor 1023, Finsolv TN and bees wax, and one or a plurality of plant oils, plant seed oils, fatty alcohols or fats, or any combination thereof, each in combined amounts that are effective for collectively forming a base composition in a sold form having an ability to function effectively as a topically-applied carrier vehicle for the active agents.

5. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, comprising FANCOL VB, Natunola Castor 1023, Finsolv TN, bees wax and one or a plurality of flavorings, and one or a plurality of plant oils, plant seed oils, fatty alcohols or fats, or any combination thereof, each in combined amounts that are effective for collectively forming a base composition in a sold form having an ability to function effectively as a topically-applied carrier vehicle for the active agents, and wherein the base composition does not have a bitter taste or odor, has no distinctive taste or odor or has a pleasant taste or odor.

6. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, consisting essentially of FANCOL VB, Natunola Castor 1023, Finsolv TN, bees wax and one or a plurality of flavorings, and one or a plurality of plant oils, plant seed oils, fatty alcohols or fats, or any combination thereof, each in combined amounts that are effective for collectively forming a base composition in a sold form having an ability to function effectively as a topically-applied carrier vehicle for the active agents, and wherein the base composition does not have a bitter taste or odor, has no distinctive taste or odor or has a pleasant taste or odor.

7. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, comprising:

(a) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(b) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 39 weight percent;

(c) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(d) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 43 weight percent;

(e) optionally, one or a plurality of plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0 to about 24 weight percent;

(f) optionally, one or a plurality of fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0 to about 22 weight percent;

(g) optionally, one or a plurality of fats, wherein the fats are present in the base composition in a combined amount ranging from about 0 to about 9 weight percent; and

(h) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in a combined amount ranging from about 0 to about 3.5 weight percent;

wherein the base composition is present in a sold form that may, optionally, soften upon an application of heat thereto and has an ability to function effectively as a topically-applied carrier vehicle for the active agents.

8. A base composition of claim 7, wherein the base composition includes a plant oil or plant seed oil in an amount ranging form about 10 to about 15 weight percent, a fatty alcohol in an amount ranging from about 18 to about 22 weight percent or a fat in an amount ranging from about 4 to about 9 weight percent, or any combination thereof.

9. A base composition of claim 7, wherein the base composition includes a plant oil or plant seed oil, and such oil is castor oil, a fatty alcohol, and such fatty alcohol is stearyl alcohol, or a fat, and such fat is cocoa butter, or any combination thereof.

10. A base composition of claim 9, wherein the base composition includes castor oil in an amount ranging from about 10 to about 15 weight percent, stearyl alcohol in an amount ranging from about 18 to about 22 weight percent, or cocoa butter in an amount ranging from about 4 to about 9 weight percent, or any combination thereof.

11. A base composition of claim 7, wherein the base composition includes at least one flavoring, and wherein the flavoring is present in an amount ranging from about 0.1 to about 3.5 weight percent.

12. A base composition of claim 7, wherein the base composition has an ability to penetrate one or a plurality of layers of a mammal'"'"'s skin.

13. A base composition of claim 12, wherein the base composition has an ability to penetrate the epidermis and dermis of the mammal'"'"'s skin.

14. A base composition of claim 7, wherein the base composition, when applied to a mammal'"'"'s skin, provides a barrier on a surface of the skin that reduces or prevents transepidermal water loss from the skin, protects the skin from one or a plurality of harmful or damaging environmental conditions or elements, or both.

15. A base composition of claim 7, wherein the base composition has a feel to a mammal'"'"'s skin that is smooth and not greasy, gritty or tacky.

16. A base composition of claim 7, wherein the base composition has:

(i) no particular or significant taste or odor;

or (ii) a pleasant taste or odor, or both.

17. A base composition of claim 7, wherein the base composition may not easily be removed from a mammal'"'"'s skin by wiping, patting or rubbing.

18. A base composition of claim 7, wherein the base composition does not crack at an environmental temperature ranging from about 0°

F. to about 32°

F., and retains its solid form and shape at an environmental temperature up to about 122°

F.

19. A base composition of claim 18, wherein the base composition retains its solid form and shape at an environmental temperature up to about 100°

F.

20. A base composition of claim 7, wherein the base composition remains physically and chemically stable for a period of at least two years.

21. A base composition of claim 7, wherein the base composition does not include petroleum jelly, water, a surfactant, an emulsifier, lidocaine hydrochloride, aluminum fluoride, propylene glycol, retinol or a retinol derivative.

22. A base composition of claim 7, wherein the base composition has one of the following formulations:

23. A base composition of claim 7, wherein the base composition is in the shape of a cylinder.

24. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, consisting essentially of

(a) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(b) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 39 weight percent;

(c) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(d) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 43 weight percent;

(e) optionally, one or a plurality of plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0 to about 24 weight percent;

(f) optionally, one or a plurality of fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0 to about 22 weight percent;

(g) optionally, one or a plurality of fats, wherein the fats are present in the base composition in a combined amount ranging from about 0 to about 9 weight percent; and

(h) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in a combined amount ranging from about 0 to about 3.5 weight percent;

wherein the base composition is present in a sold form that may, optionally, soften upon an application of heat thereto and has an ability to function effectively as a topically-applied carrier vehicle for the active agents.

25. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, comprising:

(a) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(b) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 20 weight percent;

(c) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(d) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 22 weight percent;

(e) one or more plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0.1 to about 24 weight percent;

(f) one or more fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0.1 to about 22 weight percent;

(g) one or more fats, wherein the fats are present in the base composition in a combined amount ranging from about 0.1 to about 9 weight percent; and

(h) optionally, one or more flavorings, wherein the flavorings are present in the base composition in an amount ranging from about 0 to about 3.5 weight percent;

wherein the base composition is present in a sold form that may, optionally, soften upon an application of heat thereto and has an ability to function effectively as a topically-applied carrier vehicle for the active agents.

26. A base composition of claim 25, wherein the plant oil or plant seed oil is present in an amount ranging form about 10 to about 15 weight percent, the fatty alcohol is present in an amount ranging from about 18 to about 22 weight percent and the fat is present in an amount ranging from about 4 to about 9 weight percent.

27. A base composition of claim 25, wherein the plant oil or plant seed oil is castor oil, the fatty alcohol is stearyl alcohol and the fat is cocoa butter.

28. A base composition of claim 26, wherein the plant oil or plant seed oil is castor oil, the fatty alcohol is stearyl alcohol and the fat is cocoa butter.

29. A base composition of claim 25, wherein the base composition includes castor oil in an amount ranging from about 10 to about 15 weight percent, stearyl alcohol in an amount ranging from about 18 to about 22 weight percent, or cocoa butter in an amount ranging from about 4 to about 9 weight percent, or any combination thereof.

30. A base composition of claim 25, wherein the base composition includes at least one flavoring, and wherein the flavoring is present in an amount ranging from about 0.1 to about 3.5 weight percent.

31. A base composition of claim 25, wherein the base composition has an ability to penetrate one or a plurality of layers of a mammal'"'"'s skin.

32. A base composition of claim 31, wherein the base composition has an ability to penetrate the epidermis and dermis of the mammal'"'"'s skin.

33. A base composition of claim 25, wherein the base composition, when applied to a mammal'"'"'s skin, provides a barrier on a surface of the skin that reduces or prevents transepidermal water loss from the skin, protects the skin from one or a plurality of harmful or damaging environmental conditions or elements, or both.

34. A base composition of claim 25, wherein the base composition has a feel to a mammal'"'"'s skin that is smooth and not greasy, gritty or tacky.

35. A base composition of claim 25 wherein the base composition has:

(i) no particular or significant taste or odor;

or (ii) a pleasant taste or odor, or both.

36. A base composition of claim 25, wherein the base composition may not easily be removed from a mammal'"'"'s skin by wiping, patting or rubbing.

37. A base composition of claim 25, wherein the base composition does not crack at an environmental temperature ranging from about 0°

F. to about 32°

F., and retains its solid form and shape at an environmental temperature up to about 122°

F.

38. A base composition of claim 37, wherein the base composition does not crack at an environmental temperature ranging from about 0°

F. to about 32°

F., and retains its solid form and shape at an environmental temperature up to about 100°

F.

39. A base composition of claim 25, wherein the base composition remains physically and chemically stable for a period of at least two years.

40. A base composition of claim 25, wherein the base composition does not include petroleum jelly, water, a surfactant, an emulsifier, lidocaine hydrochloride, aluminum fluoride, propylene glycol, retinol or a retinol derivative.

41. A base composition of claim 25, wherein the base composition is in the shape of a cylinder or stick.

42. A topical base composition in a solid form for use as a carrier vehicle for one or a plurality of active agents, consisting essentially of

(a) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(b) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 20 weight percent;

(c) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(d) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 22 weight percent;

(e) one or more plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0.1 to about 24 weight percent;

(f) one or more fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0.1 to about 22 weight percent;

(g) one or more fats, wherein the fats are present in the base composition in a combined amount ranging from about 0.1 to about 9 weight percent; and

(h) optionally, one or more flavorings, wherein the flavorings are present in the base composition in an amount ranging from about 0 to about 3.5 weight percent;

wherein the base composition is present in a sold form that may, optionally, soften upon an application of heat thereto and has an ability to function effectively as a topically-applied carrier vehicle for the active agents.

43. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising:

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount that is effective for repairing, improving or healing the mammal'"'"'s skin, or causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or any combination thereof, after one or more topical applications of the composition to the mammal'"'"'s skin; and

(b) a base composition, wherein the base composition is present in the composition in an amount that is effective for permitting the base composition to function effectively as a carrier vehicle for the active agents when topically applied to the mammal'"'"'s skin, and wherein the base composition includes FANCOL VB, Natunola Castor 1023, Finsolv TN and bees wax, each in amounts that are effective for collectively forming the base composition in a sold form;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

44. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, consisting essentially of

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount that is effective for repairing, improving or healing the mammal'"'"'s skin, or causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or any combination thereof, after one or more topical applications of the composition to the mammal'"'"'s skin;

and

(b) a base composition, wherein the base composition is present in the composition in an amount that is effective for permitting the base composition to function effectively as a carrier vehicle for the active agents when topically applied to the mammal'"'"'s skin, and wherein the base composition includes FANCOL VB, Natunola Castor 1023, Finsolv TN and bees wax, each in amounts that are effective for collectively forming the base composition in a sold form;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

45. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or any combination thereof, comprising:

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount that is effective for repairing, improving or healing the mammal'"'"'s skin, or causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, after one or more topical applications of the composition to the mammal'"'"'s skin; and

(b) a base composition, wherein the base composition is present in the composition in an amount that is effective for permitting the base composition to function effectively as a carrier vehicle for the active agents when topically applied to the mammal'"'"'s skin, and wherein the base composition includes FANCOL VB, Natunola Castor 1023, Finsolv TN and bees wax, and one or a plurality of plant oils, plant seed oils, fatty alcohols or fats, or any combination thereof, each in combined amounts that are effective for collectively forming together a base composition in a sold form;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

46. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or any combination thereof, consisting essentially of

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount that is effective for repairing, improving or healing the mammal'"'"'s skin, or causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, after one or more topical applications of the composition to the mammal'"'"'s skin;

and

(b) a base composition, wherein the base composition is present in the composition in an amount that is effective for permitting the base composition to function effectively as a carrier vehicle for the active agents when topically applied to the mammal'"'"'s skin, and wherein the base composition includes FANCOL VB, Natunola Castor 1023, Finsolv TN and bees wax, and one or a plurality of plant oils, plant seed oils, fatty alcohols or fats, or any combination thereof, each in combined amounts that are effective for collectively forming together a base composition in a sold form;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

47. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising:

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount that is effective for repairing, improving or healing the mammal'"'"'s skin, or causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, after one or more topical applications of the composition to the mammal'"'"'s skin; and

(b) a base composition, wherein the base composition is present in the composition in an amount that is effective for permitting the base composition to function effectively as a carrier vehicle for the active agents when topically applied to the mammal'"'"'s skin, and wherein the base composition includes FANCOL VB, Natunola Castor 1023, Finsolv TN, bees wax and one or more flavorings, and one or a plurality of plant oils, plant seed oils, fatty alcohols or fats, or any combination thereof, each in combined amounts that are effective for collectively forming together a base composition in a sold form, and wherein the base composition does not have a bitter taste or odor, has no distinctive taste or odor or has a pleasant taste or odor;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

48. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, consisting essentially of

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount that is effective for repairing, improving or healing the mammal'"'"'s skin, or causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, after one or more topical applications of the composition to the mammal'"'"'s skin;

and

(b) a base composition, wherein the base composition is present in the composition in an amount that is effective for permitting the base composition to function effectively as a carrier vehicle for the active agents when topically applied to the mammal'"'"'s skin, and wherein the base composition includes FANCOL VB, Natunola Castor 1023, Finsolv TN, bees wax and one or more flavorings, and one or a plurality of plant oils, plant seed oils, fatty alcohols or fats, or any combination thereof, each in combined amounts that are effective for collectively forming together a base composition in a sold form, and wherein the base composition does not have a bitter taste or odor, has no distinctive taste or odor or has a pleasant taste or odor;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

49. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising:

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount ranging from about 0.1 to about 5 weight percent; and

(b) a base composition, wherein the base composition is present in the composition in an amount ranging from about 95 to about 99.9 weight percent, and wherein the base composition includes;

(1) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(2) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 39 weight percent;

(3) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(4) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 43 weight percent;

(5) optionally, one or a plurality of plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0 to about 24 weight percent;

(6) optionally, one or a plurality of fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0 to about 22 weight percent;

(7) optionally, one or a plurality of fats, wherein the fats are present in the base composition in a combined amount ranging from about 0 to about 9 weight percent; and

(8) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in a combined amount ranging from about 0 to about 3.5 weight percent;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin

50. A composition of claim 49, wherein the composition includes a plant oil or plant seed oil in an amount ranging form about 9.5 to about 13.5 weight percent, a fatty alcohol in an amount ranging from about 18 to about 22 weight percent or a fat in an amount ranging from about 5 to about 9 weight percent, or any combination thereof.

51. A composition of claim 49, wherein the composition includes a plant oil or plant seed oil, and such oil is castor oil, a fatty alcohol, and such fatty alcohol is stearyl alcohol, or a fat, and such fat is cocoa butter, or any combination thereof.

52. A composition of claim 51, wherein the composition includes castor oil in an amount ranging from about 9.5 to about 13 weight percent, stearyl alcohol in an amount ranging from about 18 to about 22 weight percent, or cocoa butter in an amount ranging from about 5 to about 9 weight percent, or any combination thereof.

53. A composition of claim 49, wherein the composition includes at least one flavoring, and wherein the flavoring is present in an amount ranging from about 0.1 to about 3.5 weight percent.

54. A composition of claim 49, wherein the composition has an ability to penetrate one or a plurality of layers of the mammal'"'"'s skin.

55. A composition of claim 54, wherein the composition has an ability to penetrate the epidermis and dermis of the mammal'"'"'s skin.

56. A composition of claim 49, wherein the active agent(s) have an ability to repair, improve or partially or fully heal the mammal'"'"'s skin by exhibiting their activities deep within a plurality of layers of, and tissues present in, the mammal'"'"'s skin.

57. A composition of claim 52, wherein the active agent(s) have an ability to repair, improve or partially or fully heal the mammal'"'"'s skin by exhibiting their activities in the epidermis and dermis of the mammal'"'"'s skin.

58. A composition of claim 49, wherein the composition, when applied to a mammal'"'"'s skin, provides a barrier on a surface of the skin that reduces or prevents transepidermal water loss from the skin, protects the skin from one or a plurality of harmful or damaging environmental conditions or elements, or both.

59. A composition of claim 49, wherein the composition has a feel to a mammal'"'"'s skin that is smooth and not greasy, gritty or tacky.

60. A composition of claim 49, wherein the composition has:

(i) no particular or significant taste or odor;

or (ii) a pleasant taste or odor, or both.

61. A composition of claim 49, wherein the composition may not easily be removed from a mammal'"'"'s skin by wiping, patting or rubbing.

62. A composition of claim 49, wherein the composition does not crack at an environmental temperature ranging from about 0°

F. to about 32°

F., and retains its solid form and shape at an environmental temperature up to about 122°

F.

63. A composition of claim 62, wherein the composition retains its solid form and shape at an environmental temperature up to about 100°

F.

64. A composition of claim 49, wherein the composition remains physically and chemically stable for a period of at least two years.

65. A composition of claim 49, wherein one of the active agents is hydrocortisone.

66. A composition of claim 65, wherein the composition contains only one active agent, and wherein the active agent is hydrocortisone.

67. A composition of claim 65, wherein the composition has:

(i) no bitter taste or odor;

or (ii) a pleasant taste or odor, or both.

68. A composition of claim 66, wherein the composition has:

(i) no bitter taste or odor;

or (ii) a pleasant taste or odor, or both.

69. A composition of claim 49, wherein the composition does not include petroleum jelly, water, a surfactant, an emulsifier, lidocaine hydrochloride, aluminum fluoride, propylene glycol, retinol or a retinol derivative.

70. A composition of claim 49, wherein the active agents are present in a combined amount ranging from about 0.5 to about 3 weight percent.

71. A composition of claim 49, wherein the active agents are present in a combined amount ranging from about 0.8 to about 2 weight percent.

72. A composition of claim 49, wherein the composition is in the shape of a cylinder or stick.

151. A method for repairing, improving or healing a skin disorder, disease or condition of a mammal, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising topically applying to the mammal'"'"'s skin on a regular basis at least two applications of a composition of claim 49, wherein the amount of the composition that is applied to the skin of the mammal is an amount that is effective for repairing, improving or healing a skin disorder, disease or condition of the mammal, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, and wherein the composition is optionally heated to a temperature above ambient temperature prior to topically applying the composition to the mammal'"'"'s skin.

73. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, consisting essentially of:

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount ranging from about 0.1 to about 5 weight percent; and

(b) a base composition, wherein the base composition is present in the composition in an amount ranging from about 95 to about 99.9 weight percent, and wherein the base composition includes;

(1) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(2) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 39 weight percent;

(3) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(4) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 43 weight percent;

(5) optionally, one or a plurality of plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0 to about 24 weight percent;

(6) optionally, one or a plurality of fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0 to about 22 weight percent;

(7) optionally, one or a plurality of fats, wherein the fats are present in the base composition in a combined amount ranging from about 0 to about 9 weight percent; and

(8) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in a combined amount ranging from about 0 to about 3.5 weight percent;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

74. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising:

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount ranging from about 0.1 to about 5 weight percent; and

(b) a base composition, wherein the base composition is present in the composition in an amount ranging from about 95 to about 99.9 weight percent, and wherein the base composition includes;

(1) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(2) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 20 weight percent;

(3) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(4) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 22 weight percent;

(5) one or more plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0.1 to about 24 weight percent;

(6) one or more fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0.1 to about 22 weight percent;

(7) one or more fats, wherein the fats are present in the base composition in a combined amount ranging from about 0.1 to about 9 weight percent; and

(8) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in an amount ranging from about 0 to about 3.5 weight percent;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

75. A composition of claim 74, wherein the plant oil or plant seed oil is castor oil, the fatty alcohol is stearyl alcohol, or the fat is cocoa butter, or any combination thereof.

76. A composition of claim 74, wherein the composition includes castor oil in an amount ranging from about 9.5 to about 13 weight percent, stearyl alcohol in an amount ranging from about 18 to about 22 weight percent, or cocoa butter in an amount ranging from about 5 to about 9 weight percent, or any combination thereof.

77. A composition of claim 74, wherein the composition includes at least one flavoring, and wherein the flavoring is present in an amount ranging from about 0.1 to about 3.5 weight percent.

78. A composition of claim 74, wherein the composition has an ability to penetrate one or a plurality of layers of the mammal'"'"'s skin.

79. A composition of claim 78, wherein the composition has an ability to penetrate the epidermis and dermis of the mammal'"'"'s skin.

80. A composition of claim 74, wherein the active agent(s) have an ability to repair, improve or partially or fully heal the mammal'"'"'s skin by exhibiting their activities deep within a plurality of layers of, and tissues present in, the mammal'"'"'s skin.

81. A composition of claim 76, wherein the active agent(s) have an ability to repair, improve, or partially or fully heal the mammal'"'"'s skin by exhibiting their activities in the epidermis and dermis of the mammal'"'"'s skin.

82. A composition of claim 74, wherein the composition, when applied to a mammal'"'"'s skin, provides a barrier on a surface of the skin that reduces or prevents transepidermal water loss from the skin, protects the skin from one or a plurality of harmful or damaging environmental conditions or elements, or both.

83. A composition of claim 74, wherein the composition has a feel to a mammal'"'"'s skin that is smooth and not greasy, gritty or tacky.

84. A composition of claim 74, wherein the composition has:

(i) no particular or significant taste or odor;

or (2) a pleasant taste or odor, or both.

85. A composition of claim 74, wherein the composition may not easily be removed from a mammal'"'"'s skin by wiping, patting or rubbing.

86. A composition of claim 74, wherein the composition does not crack at an environmental temperature ranging from about 0°

F. to about 32°

F., and retains its solid form and shape at an environmental temperature up to about 122°

F.

87. A composition of claim 86, wherein the composition retains its solid form and shape at an environmental temperature up to about 100°

F.

88. A composition of claim 74, wherein the composition remains physically and chemically stable for a period of at least two years.

89. A composition of claim 74, wherein one of the active agents is hydrocortisone.

90. A composition of claim 74, wherein the composition contains only one active agent, and wherein the active agent is hydrocortisone.

91. A composition of claim 89, wherein the composition has:

(i) no bitter taste or odor;

or (ii) a pleasant taste or odor, or both.

92. A composition of claim 90, wherein the composition has:

(i) no bitter taste or odor;

or (ii) a pleasant taste or odor, or both.

93. A composition of claim 74, wherein the composition has an ability to penetrate one or a plurality of layers of the mammal'"'"'s skin.

94. A composition of claim 93, wherein the composition has an ability to penetrate the epidermis and dermis of the mammal'"'"'s skin.

95. A composition of claim 74, wherein the active agent(s) have an ability to repair, improve or partially or fully heal the mammal'"'"'s skin by exhibiting their activities deep within a plurality of layers of, and tissues present in, the mammal'"'"'s skin.

96. A composition of claim 76, wherein the active agent(s) have an ability to repair, improve or partially or fully heal the mammal'"'"'s skin by exhibiting their activities in the epidermis and dermis of the mammal'"'"'s skin.

97. A composition of claim 74, wherein the composition, when applied to a mammal'"'"'s skin, provides a barrier on a surface of the skin that reduces or prevents transepidermal water loss from the skin, protects the skin from one or a plurality of harmful or damaging environmental conditions or elements, or both.

98. A composition of claim 74, wherein the composition has a feel to a mammal'"'"'s skin that is smooth and not greasy, gritty or tacky.

99. A composition of claim 74, wherein the composition has:

(i) no particular or significant taste or odor;

or (2) a pleasant taste or odor, or both.

100. A composition of claim 74, wherein the composition may not easily be removed from a mammal'"'"'s skin by wiping, patting or rubbing.

101. A composition of claim 74, wherein the composition does not include petroleum jelly, water, a surfactant, an emulsifier, lidocaine hydrochloride, aluminum fluoride, propylene glycol, retinol or a retinol derivative.

102. A composition of claim 74, wherein the active agents are present in a combined amount ranging from about 0.5 to about 3 weight percent.

103. A composition of claim 74, wherein the active agents are present in a combined amount ranging from about 0.8 to about 2 weight percent.

104. A composition of claim 74, wherein the composition is in the shape of a cylinder or stick.

152. A method for repairing, improving or healing a skin disorder, disease or condition of a mammal, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising topically applying to the mammal'"'"'s skin on a regular basis at least two applications of a composition of claim 74, wherein the amount of the composition that is applied to the skin of the mammal is an amount that is effective for repairing, improving or healing a skin disorder, disease or condition of the mammal, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, and wherein the composition is optionally heated to a temperature above ambient temperature prior to topically applying the composition to the mammal'"'"'s skin.

105. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, consisting essentially of:

(a) one or a plurality of active agents, wherein the active agents are present in the composition in a combined amount ranging from about 0.1 to about 5 weight percent; and

(b) a base composition, wherein the base composition is present in the composition in an amount ranging from about 95 to about 99.9 weight percent, and wherein the base composition includes;

(1) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(2) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 20 weight percent;

(3) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(4) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 22 weight percent;

(5) one or more plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0.1 to about 24 weight percent;

(6) one or more fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0.1 to about 22 weight percent;

(7) one or more fats, wherein the fats are present in the base composition in a combined amount ranging from about 0.1 to about 9 weight percent; and

(8) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in an amount ranging from about 0 to about 3.5 weight percent;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

150. A composition of claim 49, claim 73, claim 74 or claim 105 wherein one of the active agents is selected from the group consisting of:

Clobetasol propionate 0.05%

Betamethasone dipropionate 0.25%

Halobetasol proprionate 0.05%

Diflorasone diacetate 0.05%

Fluocinonide 0.05%

Halcinonide 0.05%

Amcinonide 0.05%

Desoximetasone 0.25%

Triamcinolone acetonide 0.5%

Mometasone furoate 0.1%

Fluticasone propionate 0.005%

Betamethasone dipropionate 0.05%

Fluocinolone acetonide 0.01-0.2%

Hydrocortisone valerate 0.2%

Hydrocortisone butyrate 0.1%

Flurandrenolide 0.05%

Triamcinolone acetonide 0.1%

Mometasone furoate 0.1%

Triamcinolone acetonide 0.1%

Fluticasone propionate 0.05%

Desonide 0.05%

Fluocinolone acetonide 0.025%

Hydrocortisone valerate 0.2%

Prednicarbate 0.05%

Triamcinolone acetonide 0.025%

Fluocinolone acetonide 0.01%

Desonide 0.05%

Hydrocortisone 2.5%

Hydrocortisone 1%

Topical erythromycin

Topical mupirocin

Topical retapamulin

Topical bacitracin/polymyxin B

Topical bacitracin/neomycin/polymyxin B

Topical sulfacetamide sodium/urea

Natamycin

Rimocidin

Filipin

Nystatin

Amphotericin B

Candicin

Hamycin

Miconazole, miconazole nitrate

Ketoconazole

Clotrimazole

Econazole

Bifonazole

Butoconazole

Fenticonazole

Isoconazole

Oxiconazole

Sertaconazole

Sulconazole

Tioconazole

Fluconazole

Itraconazole

Isavuconazole

Ravuconazole

Posaconazole

Voriconazole

Terconazole

Abafungin

Terbinafine

Naftifine

Butenafine

Anidulafungin

Caspofungin

Micafungin

Polygodial

Ciclopirox, ciclopirox olamine

Tolnaftate

Undecylenic acid

Flucytosine, 5-fluorocytosine

Griseofulvin

Haloprogin

Sodium bicarbonate

Pimecrolimus 1% Cream

Tacrolimus 0.1% ointment

Clemastine

Diphenhydramine

Doxylamine

Loratadine

Desloratadine

Fexofenadine

Pheniramine

Cetirizine

Ebastine

Promethazine

Chlorpheniramine

Levocetirizine

Olopatadine

Quetiapine

Meclizine

Dimenhydrinate

embramine

dimethindene

dexchlorpheniramine

Vitamin C

Cimetidine

Famotidine

Ranitidine

Nizatidine

Roxatidine

Lafutidine

A-349,821

ABT-239

Ciproxifan

Clobenpropit

Thioperamide

Thioperamide

JNJ 7777120

VUF-6002

Cromoglicate

Nedocromil

a β

2 adrenergic agonist

Acetaminophen

Diclofenac

Diflunisal

Etodolac

Fenoprofen

Flurbiprofen

Ibuprofen

Indomethacin

Ketoprofen

Ketorolac

Meclofenamate

Mefenamic Acid

Meloxicam

Nabumetone

Naproxen

Oxaprozin

Phenylbutazone

Piroxicam

Sulindac

Tolmetin

Celecoxib

Buprenorphine

Butorphanol

Codeine

Hydrocodone

Hydromorphone

Levorphanol

Meperidine

Methadone

Morphine

Nalbuphine

Oxycodone

Oxymorphone

Pentazocine

Propoxyphene

Tramadol

Tramadol and Acetaminophen

Butalbital Acetaminophen, and Caffeine

Butalbital, Aspirin, and Caffeine

Butalbital, acetaminophen, caffeine, and codeine

Hydrocodone and Ibuprofen

Pentazocine/Naloxone

Acetaminophen and Codeine

Dihydrocodeine, Acetaminophen, and Caffeine

Hydrocodone and Acetaminophen

Oxycodone and Acetaminophen

Pentazocine and Acetaminophen

Propoxyphene and Acetaminophen

Aspirin, Caffein and Dihydrocodeine

Aspirin and Codeine

Hydrocodone and Aspirin

Oxycodone and Aspirin

Pentazocine and Aspirin

Propoxyphene, Aspirin, and Caffeine

Capsaicin

Benzocaine

Benzocaine/Menthol

Dibucaine

Lidocaine

Lidocaine/Prilocalne

onabotulinumtoxinA

abobotulinumtoxinA

incobotulinumtoxinA

Botulinum Toxin Type A

DEET (N,N-diethyl-m-toluamide)

Essential Oil

Icaridin

Nepetalactone

Citronella oil

Permethrin

Neem oil

Bog Myrtle

3-[N-Butyl-N-acetyl]-aminopropionic acid, ethyl ester

p-Aminobenzoic acid

Padimate O

Phenylbenzimidazole sulfonic acid

Cinoxate

Dioxybenzone

Oxybenzone

Homosalate

Menthyl anthranilate

Octocrylene

Octyl methoxycinnamate

Octyl salicylate

Sulisobenzone

Trolamine salicylate

Avobenzone

Ecamsule

Titanium dioxide

Zinc oxide

4-Methylbenzylidene camphor

Tinosorb M

Tinosorb S

Neo Heliopan AP

Mexoryl XL

Benzophenone-9

Uvinul T 150

Uvinul A Plus

Uvasorb HEB

Parsol SLX and

Isopentenyl-4-methoxycinnamate.

106. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising:

(a) hydrocortisone and, optionally, one or a plurality of other active agents, wherein the hydrocortisone and optional other active agents are present in the composition in a combined amount ranging from about 0.1 to about 5 weight percent; and

(b) a base composition, wherein the base composition is present in the composition in an amount ranging from about 95 to about 99.9 weight percent, and wherein the base composition includes;

(1) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(2) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 39 weight percent;

(3) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(4) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 43 weight percent;

(5) optionally, one or a plurality of plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0 to about 24 weight percent;

(6) optionally, one or a plurality of fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0 to about 22 weight percent;

(7) optionally, one or a plurality of fats, wherein the fats are present in the base composition in a combined amount ranging from about 0 to about 9 weight percent; and

(8) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in a combined amount ranging from about 0 to about 3.5 weight percent;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

107. A composition of claim 106, wherein the composition includes a plant oil or plant seed oil in an amount ranging form about 9.5 to about 13.5 weight percent, a fatty alcohol in an amount ranging from about 18 to about 22 weight percent or a fat in an amount ranging from about 5 to about 9 weight percent, or any combination thereof.

108. A composition of claim 106, wherein the composition includes a plant oil or plant seed oil, and such oil is castor oil, a fatty alcohol, and such fatty alcohol is stearyl alcohol, or a fat, and such fat is cocoa butter, or any combination thereof.

109. A composition of claim 108, wherein the composition includes castor oil in an amount ranging from about 9.5 to about 13 weight percent, stearyl alcohol in an amount ranging from about 18 to about 22 weight percent, or cocoa butter in an amount ranging from about 5 to about 9 weight percent, or any combination thereof.

110. A composition of claim 106, wherein the composition includes at least one flavoring, and wherein the flavoring is present in an amount ranging from about 0.1 to about 3.5 weight percent.

111. A composition of claim 106, wherein the composition has an ability to penetrate one or a plurality of layers of the mammal'"'"'s skin.

112. A composition of claim 109, wherein the composition has an ability to penetrate the epidermis and dermis of the mammal'"'"'s skin.

113. A composition of claim 106, wherein the hydrocortisone has an ability to repair, improve or partially or fully heal the mammal'"'"'s skin by exhibiting its activity deep within a plurality of layers of, and tissues present in, the mammal'"'"'s skin.

114. A composition of claim 109, wherein the hydrocortisone has an ability to repair, improve or partially or fully heal the mammal'"'"'s skin by exhibiting its activity in the epidermis and dermis of the mammal'"'"'s skin.

115. A composition of claim 106, wherein the composition, when applied to a mammal'"'"'s skin, provides a barrier on a surface of the skin that reduces or prevents transepidermal water loss from the skin, protects the skin from one or a plurality of harmful or damaging environmental conditions or elements, or both.

116. A composition of claim 106, wherein the composition has a feel to a mammal'"'"'s skin that is smooth and not greasy, gritty or tacky.

117. A composition of claim 106, wherein the composition has:

(i) no bitter taste or odor;

or (ii) a pleasant taste or odor, or both.

118. A composition of claim 106, wherein the composition may not easily be removed from a mammal'"'"'s skin by wiping, patting or rubbing.

119. A composition of claim 106, wherein the composition does not crack at an environmental temperature ranging from about 0°

F. to about 32°

F., and retains its solid form and shape at an environmental temperature up to about 122°

F.

120. A composition of claim 119, wherein the composition retains its solid form and shape at an environmental temperature up to about 100°

F.

121. A composition of claim 106, wherein the composition remains physically and chemically stable for a period of at least two years.

122. A composition of claim 106, wherein the composition does not include petroleum jelly, water, a surfactant, an emulsifier, lidocaine hydrochloride, aluminum fluoride, propylene glycol, retinol or retinol derivatives.

123. A composition of claim 106, wherein the hydrocortisone is present in an amount ranging from about 0.5 to about 3 weight percent.

124. A composition of claim 123, wherein the hydrocortisone is present in an amount ranging from about 0.8 to about 2 weight percent.

125. A composition of claim 106, wherein the composition is in the shape of a cylinder or stick.

153. A method for repairing, improving or healing a skin disorder, disease or condition of a mammal, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising topically applying to the mammal'"'"'s skin on a regular basis at least two applications of a composition of claim 106, wherein the amount of the composition that is applied to the skin of the mammal is an amount that is effective for repairing, improving or healing a skin disorder, disease or condition of the mammal, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, and wherein the composition is optionally heated to a temperature above ambient temperature prior to topically applying the composition to the mammal'"'"'s skin.

126. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, consisting essential of:

(a) hydrocortisone and, optionally, one or a plurality of other active agents, wherein the hydrocortisone and optional other active agents are present in the composition in a combined amount ranging from about 0.1 to about 5 weight percent; and

(b) a base composition, wherein the base composition is present in the composition in an amount ranging from about 95 to about 99.9 weight percent, and wherein the base composition includes;

(1) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(2) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 39 weight percent;

(3) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 25 weight percent;

(4) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 43 weight percent;

(5) optionally, one or a plurality of plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0 to about 24 weight percent;

(6) optionally, one or a plurality of fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0 to about 22 weight percent;

(7) optionally, one or a plurality of fats, wherein the fats are present in the base composition in a combined amount ranging from about 0 to about 9 weight percent; and

(8) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in a combined amount ranging from about 0 to about 3.5 weight percent;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

127. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising:

(a) hydrocortisone and, optionally, one or a plurality of other active agents, wherein the hydrocortisone and optional other active agents are present in the composition in a combined amount ranging from about 0.1 to about 5 weight percent; and

(b) a base composition, wherein the base composition is present in the composition in an amount ranging from about 95 to about 99.9 weight percent, and wherein the base composition includes;

(1) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(2) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 20 weight percent;

(3) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(4) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 22 weight percent;

(5) one or more plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0.1 to about 24 weight percent;

(6) one or more fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0.1 to about 22 weight percent;

(7) one or more fats, wherein the fats are present in the base composition in a combined amount ranging from about 0.1 to about 9 weight percent; and

(8) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in an amount ranging from about 0 to about 3.5 weight percent;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

128. A composition of claim 127, wherein the plant oil or plant seed oil is castor oil, the fatty alcohol is stearyl alcohol, or the fat is cocoa butter, or any combination thereof.

129. A composition of claim 127, wherein the composition includes castor oil in an amount ranging from about 9.5 to about 13 weight percent, stearyl alcohol in an amount ranging from about 18 to about 22 weight percent, or cocoa butter in an amount ranging from about 5 to about 9 weight percent, or any combination thereof.

130. A composition of claim 127, wherein the composition includes at least one flavoring, and wherein the flavoring is present in an amount ranging from about 0.2 to about 3 weight percent.

131. A composition of claim 127, wherein the composition has an ability to penetrate one or a plurality of layers of the mammal'"'"'s skin.

132. A composition of claim 129, wherein the composition has an ability to penetrate the epidermis and dermis of the mammal'"'"'s skin.

133. A composition of claim 127, wherein the active agent(s) have an ability to repair, improve or partially or fully heal the mammal'"'"'s skin by exhibiting their activities deep within a plurality of layers of, and tissues present in, the mammal'"'"'s skin.

134. A composition of claim 129, wherein the active agent(s) have an ability to repair, improve or partially or fully heal the mammal'"'"'s skin by exhibiting their activities in the epidermis and dermis of the mammal'"'"'s skin.

135. A composition of claim 127, wherein the composition, when applied to a mammal'"'"'s skin, provides a barrier on a surface of the skin that reduces or prevents transepidermal water loss from the skin, protects the skin from one or a plurality of harmful or damaging environmental conditions or elements, or both.

136. A composition of claim 127, wherein the composition has a feel to a mammal'"'"'s skin that is smooth and not greasy, gritty or tacky.

137. A composition of claim 127, wherein the composition has:

(i) no bitter taste or odor;

or (2) a pleasant taste or odor, or both.

138. A composition of claim 127, wherein the composition may not easily be removed from a mammal'"'"'s skin by wiping, patting or rubbing.

139. A composition of claim 127, wherein the composition does not crack at an environmental temperature ranging from about 0°

F. to about 32°

F., and retains its solid form and shape at an environmental temperature up to about 122°

F.

140. A composition of claim 139, wherein the composition retains its solid form and shape at an environmental temperature up to about 100°

F.

141. A composition of claim 127, wherein the composition remains physically and chemically stable for a period of at least two years.

142. A composition of claim 127, wherein the composition contains only one active agent, and wherein the active agent is hydrocortisone.

143. A composition of claim 127, wherein the composition does not include petroleum jelly, water, a surfactant, an emulsifier, lidocaine hydrochloride, aluminum fluoride, propylene glycol, retinol or retinol derivatives.

144. A composition of claim 127, wherein the active agents are present in a combined amount ranging from about 0.5 to about 3 weight percent.

145. A composition of claim 144, wherein the active agents are present in a combined amount ranging from about 0.8 to about 2 weight percent.

146. A composition of claim 127, wherein the composition has the following formulation:

147. A composition of claim 127, wherein the composition has the following formulation:

148. A composition of claim 127, wherein the composition is in the shape of a cylinder.

154. A method for repairing, improving or healing a skin disorder, disease or condition of a mammal, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising topically applying to the mammal'"'"'s skin on a regular basis at least two applications of a composition of claim 127, wherein the amount of the composition that is applied to the skin of the mammal is an amount that is effective for repairing, improving or healing a skin disorder, disease or condition of the mammal, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, and wherein the composition is optionally heated to a temperature above ambient temperature prior to topically applying the composition to the mammal'"'"'s skin.

149. A composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, consisting essential of:

(a) hydrocortisone and, optionally, one or a plurality of other active agents, wherein the hydrocortisone and optional other active agents are present in the composition in a combined amount ranging from about 0.1 to about 5 weight percent; and

(b) a base composition, wherein the base composition is present in the composition in an amount ranging from about 95 to about 99.9 weight percent, and wherein the base composition includes;

(1) FANCOL VB, wherein the FANCOL VB is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(2) Natunola Castor 1023, wherein the Natunola Castor 1023 is present in the base composition in an amount ranging from about 16 to about 20 weight percent;

(3) Finsolv TN, wherein the Finsolv TN is present in the base composition in an amount ranging from about 9 to about 13 weight percent;

(4) bees wax, wherein the bees wax is present in the base composition in an amount ranging from about 18 to about 22 weight percent;

(5) one or more plant oils or plant seed oils, wherein the plant oils or plant seed oils are present in the base composition in a combined amount ranging from about 0.1 to about 24 weight percent;

(6) one or more fatty alcohols, wherein the fatty alcohols are present in the base composition in a combined amount ranging from about 0.1 to about 22 weight percent;

(7) one or more fats, wherein the fats are present in the base composition in a combined amount ranging from about 0.1 to about 9 weight percent; and

(8) optionally, one or a plurality of flavorings, wherein the flavorings are present in the base composition in an amount ranging from about 0 to about 3.5 weight percent;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.

155. A method for producing a composition for topical application to the skin of a mammal for repairing, improving or healing a skin disorder, disease or condition, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness, discomfort or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, comprising the following steps in any suitable order:

(a) optionally, heating a combined amount of one or a plurality of plant oils that are sufficient, in combination with one or more other ingredients, for producing a composition in a solid form to a temperature, and for a period of time, that are effective for evenly heating the plant oils;

(b) adding an amount of FANCOL VB that is sufficient, in a combination with one or more other method ingredients, for producing a composition in a solid form to any plant oils heated in step (a), and heating the FANCOL VB at a temperature, and for a period of time, that are effective for evenly heating the FANCOL VB, and for dissolving the FANCOL VB in any such plant oils;

(c) adding an amount of Natunola Castor 1023 that is sufficient, in a combination with one or more other method ingredients, for producing a composition in a solid form to the product of step (b), and heating the Natunola Castor 1023 at a temperature, and for a period of time, that are effective for dissolving the Natunola Castor 1023 in such product;

(d) adding an amount of bees wax that is sufficient, in a combination with one or more other method ingredients, for producing a composition in a solid form to the product of step (c), and heating the bees wax at a temperature, and for a period of time, that are effective for dissolving the bees wax in such product;

(e) optionally, adding a combined amount of one or a plurality of fatty alcohols that are sufficient, in a combination with one or more other method ingredients, for producing a composition in a solid form to the product of step (d), and heating the fatty alcohols at a temperature, and for a period of time, that are effective for dissolving the fatty alcohols in such product;

(f) optionally, adding a combined amount of one or a plurality of fats that are sufficient for producing, in a combination with one or more other method ingredients, a composition in a solid form to the product of step (d) or step (e), and heating the fats at a temperature, and for a period of time, that are effective for dissolving the fats in such product;

(g) adding an amount of Finsolv TN that is sufficient, in a combination with one or more other method ingredients, for producing a composition in a solid form to the product of step (d), (e) or (f), and heating the Finsolv TN at a temperature, and for a period of time, that are effective for dissolving the Finsolv TN in such product;

(h) cooling the mixture of step (g) to a temperature that permits one or a plurality of active ingredients to be mixed therewith out significantly reducing the activities of the active ingredients, or rending them inactive;

(i) mixing a combined amount of one or a plurality of active ingredients that is sufficient, when present in a base composition in solid form, for repairing, improving or healing a skin disorder, disease or condition of a mammal, or for causing the mammal'"'"'s skin to experience a reduction in pain, soreness or itchiness, or an increase in soothing, softening or conditioning, or a combination thereof, with the product of step (h) at a temperature, and for a period of time, that is sufficient for dissolving the active ingredients in such product;

(j) optionally, cooling the mixture of step (i) to a temperature that permits one or a plurality of flavorings to be mixed therewith out significantly reducing the flavor of the flavorings, or rending them flavorless;

(k) optionally, mixing a combined amount of one or a plurality of flavorings that is sufficient, when present in the composition, for providing the composition with a desirable or distinct flavor, or for partially or fully masking one or more bitter or undesirable flavors present therein, or a combination thereof, with the product of step (i) or (j) at a temperature, and for a period of time, that is sufficient for uniformly distributing the flavorings throughout such product;

(l) optionally, determining the concentration of the active ingredients in the mixture of step (i), (j) or (k); and

(m) optionally, pouring or transferring the product of step (i), (j), (k) or (l) into one or a plurality of molds and allowing the product to harden, set or solidify therein;

wherein the composition is present in a sold form that, optionally, may soften upon an application of heat thereto and has an ability to function effectively as a topically-applied composition on the mammal'"'"'s skin.