WIDE BAND FIELD RESPONSE MEASUREMENT FOR GLUCOSE DETERMINATION
First Claim
1. A device for measuring a glucose level in living tissue, said device comprisingan electrode arrangement to be applied against said tissue,a signal generation circuit, wherein said signal generation circuit is connected to said electrode arrangement in order to generate an AC signal voltage in said electrode arrangement,a measuring circuit for measuring a response of said tissue to a field generated by said electrodes due to said signal voltage,a first temperature sensor generating a first temperature signal indicative of a temperature of said tissue,a control unit for operating said signal generation circuit, wherein said control unit is structured and adapted to operate said signal generation circuit and said measuring circuit at least at a first frequency for measuring a first electric parameter, at a second frequency for measuring a second electric parameter and at a third frequency for measuring a third electric parameter, wherein said first frequency is in a first frequency range between 1 kHz and 200 kHz, said second frequency is in a second frequency range between 0.2 MHz and 100 MHz, and said third frequency is in a third frequency range above 1 GHz,wherein said control unit is further structured and adapted to derive said glucose level from a combination of at least said first, second and third electric parameter and said first temperature parameter.
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Accused Products
Abstract
A method and device for determining the glucose level in living tissue are based on measuring the response of the tissue an electric field as well as temperature measurements. In order to improve accuracy, it has been found that measurements in at least three frequency ranges between 1 kHz and 200 kHz, 0.2 MHz an 100 MHz as well as above 1 GHz should be combined since the response of the tissue in these different frequency ranges is ruled by differing mechanisms.
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Citations
18 Claims
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1. A device for measuring a glucose level in living tissue, said device comprising
an electrode arrangement to be applied against said tissue, a signal generation circuit, wherein said signal generation circuit is connected to said electrode arrangement in order to generate an AC signal voltage in said electrode arrangement, a measuring circuit for measuring a response of said tissue to a field generated by said electrodes due to said signal voltage, a first temperature sensor generating a first temperature signal indicative of a temperature of said tissue, a control unit for operating said signal generation circuit, wherein said control unit is structured and adapted to operate said signal generation circuit and said measuring circuit at least at a first frequency for measuring a first electric parameter, at a second frequency for measuring a second electric parameter and at a third frequency for measuring a third electric parameter, wherein said first frequency is in a first frequency range between 1 kHz and 200 kHz, said second frequency is in a second frequency range between 0.2 MHz and 100 MHz, and said third frequency is in a third frequency range above 1 GHz, wherein said control unit is further structured and adapted to derive said glucose level from a combination of at least said first, second and third electric parameter and said first temperature parameter.
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13. A method for determining a glucose level in living tissue, said method comprising the steps of
applying an electrode arrangement to said tissue, applying an AC signal voltage to said electrode arrangement, said AC signal voltage comprising a first frequency between 1 kHz and 200 kHz, a second frequency between 0.2 MHz and 100 MHz, and a third frequency of at least 1 GHz, measuring a first, second and third electric parameters indicative of a response of said tissue to said AC signal voltage at said first, second and third frequencies, measuring a first temperature parameter indicative of a temperature of said tissue, and combining said first, second and third electric parameter and said temperature signal for deriving said glucose level.
Specification