STABILIZING COMPOSITIONS FOR IMMOBILIZED BIOMOLECULES
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Abstract
The present invention relates to the use of a composition comprising (a) at least three different amino acids, (b) at least two different amino acids and a saponin or (c) at least one dipeptide or tripeptide for stabilizing biomolecules immobilized on a solid carrier. The invention furthermore relates to a method for producing stabilized biomolecules, comprising embedding the biomolecules in the composition according to the invention and a method of producing a solid carrier having biomolecules attached thereto. The invention furthermore relates to a solid carrier producible or produced by the method of the invention and a method of diagnosing a disease using the carrier of the invention.
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Citations
20 Claims
- 1. (canceled)
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10. A method for producing stabilized biomolecules, comprising
(a) attaching the biomolecules to a solid carrier and (b) embedding the biomolecules in a composition selected from the group consisting of: -
(i) at least three different amino acids, (ii) at least two different amino acids and a saponin and (ii) at least one dipeptide or tripeptide so that the embedded biomolecules are partially or completely covered by the composition. - View Dependent Claims (2, 4, 5, 6, 7, 8, 9, 12, 13, 19)
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11. A method of producing a solid carrier having biomolecules attached thereto, comprising the steps of (a) attaching the biomolecules to the solid carrier and
(b) incubating the carrier of step (a) in a composition selected from the group consisting of: -
(i) at least three different amino acids, (ii) at least two different amino acids and a saponin and (ii) at least one dipeptide or tripeptide. - View Dependent Claims (14, 15, 16, 17, 18, 20)
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Specification